Design and optimization of crocetin loaded PLGA nanoparticles against diabetic nephropathy via suppression of inflammatory biomarkers: a formulation approach to …
X Yang - Drug Delivery, 2019 - Taylor & Francis
Diabetic nephropathy (DN) is a serious complication of diabetes mellitus whose expand
process is linked with the fibrosis, renal hypertrophy and inflammation. The current study …
process is linked with the fibrosis, renal hypertrophy and inflammation. The current study …
Lung inflammasome activation in SARS-CoV-2 post-mortem biopsies
L Baena Carstens, R Campos D'amico… - International Journal of …, 2022 - mdpi.com
The inflammasome complex is a key part of chronic diseases and acute infections, being
responsible for cytokine release and cell death mechanism regulation. The SARS-CoV-2 …
responsible for cytokine release and cell death mechanism regulation. The SARS-CoV-2 …
[HTML][HTML] Lung inflammasome activation in SARS-CoV-2 post-mortem biopsies
LB Carstens, RC D'amico, KF de Moura… - … Journal of Molecular …, 2022 - ncbi.nlm.nih.gov
The inflammasome complex is a key part of chronic diseases and acute infections, being
responsible for cytokine release and cell death mechanism regulation. The SARS-CoV-2 …
responsible for cytokine release and cell death mechanism regulation. The SARS-CoV-2 …
α1-Antitrypsin Modulates Lung Endothelial Cell Inflammatory Responses to TNF-α
AD Lockett, S Kimani, G Ddungu… - American journal of …, 2013 - atsjournals.org
α1-Antitrypsin (A1AT) is an acute-phase reactant, but also a major protective factor against
the development of chronic obstructive pulmonary disease, a complex disease with …
the development of chronic obstructive pulmonary disease, a complex disease with …
[HTML][HTML] Human vasculature-on-a-chip with macrophage-mediated endothelial activation: the biological effect of aerosol from heated tobacco products on monocyte …
K Ohashi, A Hayashida, A Nozawa, K Matsumura, S Ito - Toxicology in Vitro, 2023 - Elsevier
Heated tobacco products (HTPs) are expected to have the potential to reduce risks of
smoking-associated cardiovascular disease (CVD). However, mechanism-based …
smoking-associated cardiovascular disease (CVD). However, mechanism-based …
Placental blood leukocytes are functional and phenotypically different than peripheral leukocytes during human labor
R Vega-Sanchez, N Gomez-Lopez… - Journal of reproductive …, 2010 - Elsevier
Rupture of the fetal membranes during human labor is associated with an inflammatory
process localized to the maternal–fetal interface. There is evidence that specific leukocytes …
process localized to the maternal–fetal interface. There is evidence that specific leukocytes …
The impact of macrophages on endothelial cells is potentiated by cycling hypoxia: Enhanced tumor inflammation and metastasis
Cycling hypoxia (cyH), neo-angiogenesis, and tumor-associated macrophages are key
features of the tumor microenvironment. In this study, we demonstrate that cyH potentiates …
features of the tumor microenvironment. In this study, we demonstrate that cyH potentiates …
Inflammatory hypoxia induces syndecan‐2 expression through IL‐1b–mediated FOXO3a activation in colonic epithelia
Chronic inflammation is known to be a key causative factor in tumor progression, but we do
not yet fully understand the molecular mechanism through which inflammation leads to …
not yet fully understand the molecular mechanism through which inflammation leads to …
Effect of Interleukin‐17 in the activation of monocyte subsets in patients with ST‐segment elevation myocardial infarction
MG Garza-Reyes, MD Mora-Ruíz… - Journal of …, 2020 - Wiley Online Library
Interleukin‐(IL‐) 17 is increased in acute myocardial infarction (AMI) and plays a key role in
inflammatory diseases through its involvement in the activation of leukocytes. Here, we …
inflammatory diseases through its involvement in the activation of leukocytes. Here, we …
[HTML][HTML] Participation of the IKK-α/β complex in the inhibition of the TNF-α/NF-κB pathway by glycine: Possible involvement of a membrane receptor specific to …
E Contreras-Nuñez, G Blancas-Flores, M Cruz… - Biomedicine & …, 2018 - Elsevier
Glycine modulates inflammatory processes mediated by macrophages and adipocytes
through decreasing the secretion of TNF-α, IL-6, and leptin, while increasing adiponectin …
through decreasing the secretion of TNF-α, IL-6, and leptin, while increasing adiponectin …