Within the last decade, ultrasound has been “rediscovered” as a technique for brain
therapies. Modern technologies allow focusing ultrasound through the human skull for …

Sonogenetics refers to the use of genetically encoded, ultrasound-responsive mediators for
noninvasive and selective control of neural activity. It is a promising tool for studying neural …

Ultrasound has been used to non-invasively manipulate neuronal functions in humans and
other animals. However, this approach is limited as it has been challenging to target specific …

Endocytosis plays a crucial role in drug delivery for precision therapy. As a non-invasive and
spatiotemporal-controllable stimulus, ultrasound (US) has been utilized for improving drug …

Focused ultrasound stimulation (FUS) activates mechanosensitive ion channels and is
emerging as a method of noninvasive neuromodulation. In preclinical studies, FUS of the …

CRISPR/Cas9 is a revolutionary genome editing technology with the tremendous
advantages such as precisely targeting/shearing ability, low cost and convenient operation …

Non‐invasive brain stimulation has the potential to boost neuronal plasticity in the primary
motor cortex (M1), but it remains unclear whether the stimulation of both superficial and …

Sonogenetics is an emerging medical technology that uses acoustic waves to control cells
through sonosensitive mediators (SSMs) that are genetically encoded, thus remotely and …

Glioblastoma multiforme (GBM) is the most aggressive brain cancer, characterized by a
rapid and drug‐resistant progression. GBM “builds” around its primary core a genetically …

Transcranial ultrasonic stimulation (TUS) is rapidly gaining traction for non-invasive human
neuromodulation, with a pressing need to establish protocols that maximise …