Signaling pathways in cancer-associated fibroblasts and targeted therapy for cancer
F Wu, J Yang, J Liu, Y Wang, J Mu, Q Zeng… - … and Targeted Therapy, 2021 - nature.com
To flourish, cancers greatly depend on their surrounding tumor microenvironment (TME),
and cancer-associated fibroblasts (CAFs) in TME are critical for cancer occurrence and …
and cancer-associated fibroblasts (CAFs) in TME are critical for cancer occurrence and …
Cancer-associated fibroblasts: overview, progress, challenges, and directions
Q Ping, R Yan, X Cheng, W Wang, Y Zhong… - Cancer gene …, 2021 - nature.com
Tumors are one of the main causes of death in humans. The development of safe and
effective methods for early diagnosis and treatment of tumors is a difficult problem that needs …
effective methods for early diagnosis and treatment of tumors is a difficult problem that needs …
CAFs interacting with TAMs in tumor microenvironment to enhance tumorigenesis and immune evasion
G Gunaydin - Frontiers in oncology, 2021 - frontiersin.org
Cancer associated fibroblasts (CAFs) and tumor associated macrophages (TAMs) are
among the most important and abundant players of the tumor microenvironment. CAFs as …
among the most important and abundant players of the tumor microenvironment. CAFs as …
Cancer-associated fibroblasts: the chief architect in the tumor microenvironment
Stromal heterogeneity of tumor microenvironment (TME) plays a crucial role in malignancy
and therapeutic resistance. Cancer-associated fibroblasts (CAFs) are one of the major …
and therapeutic resistance. Cancer-associated fibroblasts (CAFs) are one of the major …
Poly (pentahydropyrimidine)‐Based Hybrid Hydrogel with Synergistic Antibacterial and Pro‐Angiogenic Ability for the Therapy of Diabetic Foot Ulcers
Bacterial infection and impaired angiogenesis make the treatment of diabetic foot ulcers
(DFU) extremely challenging. Cationic polymers are expected to treat infected wounds due …
(DFU) extremely challenging. Cationic polymers are expected to treat infected wounds due …
Extracellular matrix profiles determine risk and prognosis of the squamous cell carcinoma subtype of non-small cell lung carcinoma
AL Parker, E Bowman, A Zingone, BM Ryan… - Genome medicine, 2022 - Springer
Abstract Background Squamous cell carcinoma (SqCC) is a subtype of non-small cell lung
cancer for which patient prognosis remains poor. The extracellular matrix (ECM) is critical in …
cancer for which patient prognosis remains poor. The extracellular matrix (ECM) is critical in …
Cancer-associated fibroblasts: master tumor microenvironment modifiers
Simple Summary Cancer cells rely on the surrounding environment to grow and spread.
This environment contains structural components, secreted factors, immune cells, and other …
This environment contains structural components, secreted factors, immune cells, and other …
Decoding the spatiotemporal heterogeneity of tumor-associated macrophages
X Chu, Y Tian, C Lv - Molecular Cancer, 2024 - Springer
Tumor-associated macrophages (TAMs) are pivotal in cancer progression, influencing tumor
growth, angiogenesis, and immune evasion. This review explores the spatial and temporal …
growth, angiogenesis, and immune evasion. This review explores the spatial and temporal …
Cancer-associated fibroblast: role in prostate cancer progression to metastatic disease and therapeutic resistance
Prostate cancer (PCa) is one of the most common cancers in European males. Although
therapeutic approaches have changed in recent years, and several new drugs have been …
therapeutic approaches have changed in recent years, and several new drugs have been …
[HTML][HTML] FGF/FGFR signaling: From lung development to respiratory diseases
L Yang, F Zhou, D Zheng, D Wang, X Li, C Zhao… - Cytokine & growth factor …, 2021 - Elsevier
The fibroblast growth factor/fibroblast growth factor receptor (FGF/FGFR) signaling system
regulates a variety of biological processes, including embryogenesis, angiogenesis, wound …
regulates a variety of biological processes, including embryogenesis, angiogenesis, wound …