The Controversial Roles of Areca Nut: Medicine or Toxin?
PF Liu, YF Chang - International Journal of Molecular Sciences, 2023 - mdpi.com
Areca nut (AN) is used for traditional herbal medicine and social activities in several
countries. It was used as early as about AD 25-220 as a remedy. Traditionally, AN was …
countries. It was used as early as about AD 25-220 as a remedy. Traditionally, AN was …
Identification of 5-nitroindazole as a multitargeted inhibitor for CDK and transferase kinase in lung cancer: a multisampling algorithm-based structural study
Lung cancer is the second most common cancer, which is the leading cause of cancer death
worldwide. The FDA has approved almost 100 drugs against lung cancer, but it is still not …
worldwide. The FDA has approved almost 100 drugs against lung cancer, but it is still not …
Harnessing machine learning potential for personalised drug design and overcoming drug resistance
MA Hakami - Journal of Drug Targeting, 2024 - Taylor & Francis
Drug resistance in cancer treatment presents a significant challenge, necessitating
innovative approaches to improve therapeutic efficacy. Integrating machine learning (ML) in …
innovative approaches to improve therapeutic efficacy. Integrating machine learning (ML) in …
Unveiling the multitargeted repurposing potential of taxifolin (dihydroquercetin) in cervical cancer: An extensive MM\GBSA-based screening, and MD simulation study
Cervical cancer is a significant cause of morbidity and mortality in women worldwide.
Despite the availability of effective therapies, the development of drug resistance and …
Despite the availability of effective therapies, the development of drug resistance and …
Unveiling the multitargeted potency of Sodium Danshensu against cervical cancer: a multitargeted docking-based, structural fingerprinting and molecular dynamics …
Cervical Cancer (CC) is one of the most common types of cancer in women worldwide, with
a significant number of deaths reported yearly. Despite the various treatment options …
a significant number of deaths reported yearly. Despite the various treatment options …
Computational analysis of potential drug-like compounds from Solanum torvum - A promising phytotherapeutics approach for the treatment of diabetes
AA Choudhury, DR V - Journal of Biomolecular Structure and …, 2023 - Taylor & Francis
Diabetes mellitus (DM) is a global pandemic that is characterized by high blood glucose
levels. Conventional treatments have limitations, leading to the search for natural …
levels. Conventional treatments have limitations, leading to the search for natural …
Hyaluronic acid-covered ferric ion-rich nanobullets with high zoledronic acid payload for breast tumor-targeted chemo/chemodynamic therapy
NT Yeh, TC Lin, IJ Liu, SH Hu, TC Hsu, HY Chin… - International Journal of …, 2024 - Elsevier
Due to the heterogeneity of the tumor microenvironment, the clinical efficacy of tumor
treatment is not satisfied, highlighting the necessity for new strategies to tackle this issue. To …
treatment is not satisfied, highlighting the necessity for new strategies to tackle this issue. To …
Reporting multitargeted potency of Tiaprofenic acid against lung cancer: Molecular fingerprinting, MD simulation, and MTT-based cell viability assay studies
Lung Cancer (LC) is among the most death-causing cancers, has caused the most
destruction and is a gender-neutral cancer, and WHO has kept this cancer on its priority list …
destruction and is a gender-neutral cancer, and WHO has kept this cancer on its priority list …
Unveiling the multitargeted potential of deprodone and control comparison with linezolid against hydrolase and transferase enzymes of methicillin-resistant …
FM Almufarriji, BS Alotaibi, AS Alamri… - International Journal of …, 2024 - Elsevier
Abstract Staphylococcus aureus (S. aureus), commonly found on the skin and nose, causes
minor skin conditions to life-threatening diseases, including boils or impetigo, pneumonia …
minor skin conditions to life-threatening diseases, including boils or impetigo, pneumonia …
Unrevealing the multitargeted potency of 3-1-BCMIYPPA against lung cancer structural maintenance and suppression proteins through pharmacokinetics, QM-DFT …
Lung cancer, a relentless and challenging disease, demands unwavering attention in drug
design research. Single-target drugs have yielded limited success, unable to effectively …
design research. Single-target drugs have yielded limited success, unable to effectively …