Targeting NMDA receptors at the neurovascular unit: Past and future treatments for central nervous system diseases

C Seillier, F Lesept, O Toutirais, F Potzeha… - International journal of …, 2022 - mdpi.com
The excitatory neurotransmission of the central nervous system (CNS) mainly involves
glutamate and its receptors, especially N-methyl-D-Aspartate receptors (NMDARs). These …

Dynamic microtubule arrays in leukocytes and their role in cell migration and immune synapse formation

A Kopf, E Kiermaier - Frontiers in cell and developmental biology, 2021 - frontiersin.org
The organization of microtubule arrays in immune cells is critically important for a properly
operating immune system. Leukocytes are white blood cells of hematopoietic origin, which …

Quantification of strand accessibility in biostable DNA origami with single-staple resolution

AS Eklund, A Comberlato, IA Parish, R Jungmann… - ACS …, 2021 - ACS Publications
DNA-based nanostructures are actively gaining interest as tools for biomedical and
therapeutic applications following the recent development of protective coating strategies …

Click‐Chemistry‐Mediated Cell Membrane Glycopolymer Engineering to Potentiate Dendritic Cell Vaccines

H Yang, Z Xiong, X Heng, X Niu, Y Wang… - Angewandte …, 2024 - Wiley Online Library
Dendritic cell vaccine (DCV) holds great potential in tumor immunotherapy owing to its
potent ability in eliciting tumor‐specific immune responses. Aiming at engineering enhanced …

Exploring Mast Cell–CD8 T Cell Interactions in Inflammatory Skin Diseases

Y Chen, CEM Griffiths, S Bulfone-Paus - International Journal of …, 2023 - mdpi.com
The skin is exposed to environmental challenges and contains skin-resident immune cells,
including mast cells (MCs) and CD8 T cells that act as sentinels for pathogens and …

Next‐generation pathology detection of T cell–antigen‐presenting cell immune synapses in human liver allografts

MA Wood‐Trageser, D Lesniak, A Gambella… - Hepatology, 2023 - journals.lww.com
Next‐generation pathology detection of T cell–antigen‐presen... : Hepatology Next‐generation
pathology detection of T cell–antigen‐presenting cell immune synapses in human liver …

SKAP2—A molecule at the crossroads for integrin signalling and immune cell migration and function

M Wilmink, MR Spalinger - Biomedicines, 2023 - mdpi.com
Src-kinase associated protein 2 (SKAP2) is an intracellular scaffolding protein that is broadly
expressed in immune cells and is involved in various downstream signalling pathways …

The development and application of opto-chemical tools in the zebrafish

Z Feng, B Ducos, P Scerbo, I Aujard, L Jullien… - Molecules, 2022 - mdpi.com
The zebrafish is one of the most widely adopted animal models in both basic and
translational research. This popularity of the zebrafish results from several advantages such …

Role of lipids in morphogenesis of T-cell microvilli

M Cebecauer - Frontiers in immunology, 2021 - frontiersin.org
T cells communicate with the environment via surface receptors. Cooperation of surface
receptors regulates T-cell responses to diverse stimuli. Recently, finger-like membrane …

Tbc1d10c is a selective, constitutive suppressor of the CD8 T-cell anti-tumor response

AO Cohen, SH Woo, J Zhang, J Cho, ME Ruiz… - …, 2022 - Taylor & Francis
Cancer immunotherapy approaches target signaling pathways that are highly synonymous
between CD4 and CD8 T-cell subsets and, therefore, often stimulate nonspecific lymphocyte …