Consumption of a Western Diet (WD) that is high in saturated fat and added sugars
negatively impacts cognitive function, particularly mnemonic processes that rely on the …

The brain-derived neurotrophic factor (BDNF) is a protein mainly synthetized in the neurons.
Early evidence showed that BDNF participates in cognitive processes as measured at the …

Background Western-style diets arouse neuroinflammation and impair emotional and
cognitive behavior in humans and animals. Our previous study showed that a high-fructose …

Mitochondria are important for providing cellular energy ATP through the oxidative
phosphorylation pathway. They are also critical in regulating many cellular functions …

Glucose is a major energy source for the entire body, while fructose metabolism occurs
mainly in the liver. Fructose consumption has increased over the last decade globally and is …

The fructose survival hypothesis proposes that obesity and metabolic disorders may have
developed from over-stimulation of an evolutionary-based biologic response (survival …

The loss of cognitive function in Alzheimer's disease is pathologically linked with
neurofibrillary tangles, amyloid deposition, and loss of neuronal communication. Cerebral …

Fructose consumption has drastically increased during the last decades due to the extensive
commercial use of high-fructose corn syrup as a sweetener for beverages, snacks and …

In recent decades, traditional eating habits have been replaced by a more globalized diet,
rich in saturated fatty acids and simple sugars. Extensive evidence shows that these dietary …

Non-alcoholic steatohepatitis (NASH) is one of the most prevalent diseases worldwide.
While it has been suggested to cause nervous impairment, its neurophysiological basis …