This review presents lower body negative pressure (LBNP) as a unique tool to investigate
the physiology of integrated systemic compensatory responses to altered hemodynamic …

Spaceflight and its associated stressors, such as microgravity, radiation exposure,
confinement, circadian derailment and disruptive workloads represent an unprecedented …

Multiple transitions between gravity levels will occur during planetary exploration missions.
In reaction to these gravitational transitions, physiological adaptation will be initiated …

Astronauts in microgravity experience multi-system deconditioning, impacting their inflight
efficiency and inducing dysfunctions upon return to Earth gravity. To fill the sex gap of …

Weightlessness and physical inactivity have deleterious cardiovascular effects. The space
environment and its ground-based models offer conditions to study the cardiovascular …

Abstract Space exploration objectives will soon move from low Earth orbit to distant
destinations like Moon and Mars. The present work provides an up-to-date roadmap that …

During head-down tilt bed rest (HDT) the cardiovascular system is subject to headward fluid
shifts. The fluid shift phenomenon is analogous to weightlessness experienced during …

To understand fundamental mechanisms associated with post-flight orthostatic intolerance
we investigated the interaction between the cardiovascular and postural functions before …

As part of the first Canadian aging and inactivity study (CAIS) we assessed the efficacy of
space-based exercise countermeasures for maintenance of cardiac and muscle-pump …

Simple Summary Syncope is a medical condition triggered by short-lived interruption of the
oxygen supply to the brain, which may result in free fall or accidents. The diagnosis of …