[HTML][HTML] Acute kidney injury from sepsis: current concepts, epidemiology, pathophysiology, prevention and treatment

S Peerapornratana, CL Manrique-Caballero… - Kidney international, 2019 - Elsevier
Sepsis-associated acute kidney injury (S-AKI) is a frequent complication of the critically ill
patient and is associated with unacceptable morbidity and mortality. Prevention of S-AKI is …

Pharmacology behind common drug nephrotoxicities

MA Perazella - Clinical Journal of the American Society of …, 2018 - journals.lww.com
Patients are exposed to numerous prescribed and over-the-counter medications.
Unfortunately, drugs remain a relatively common cause of acute and chronic kidney injury. A …

Effect of vancomycin or daptomycin with vs without an antistaphylococcal β-lactam on mortality, bacteremia, relapse, or treatment failure in patients with MRSA …

SYC Tong, DC Lye, D Yahav, A Sud, JO Robinson… - Jama, 2020 - jamanetwork.com
Importance Methicillin-resistantStaphylococcus aureus (MRSA) bacteremia is associated
with mortality of more than 20%. Combining standard therapy with a β-lactam antibiotic has …

Nephrotoxicity from vancomycin combined with piperacillin-tazobactam: a comprehensive review

M Blair, JM Côté, A Cotter, B Lynch… - American journal of …, 2021 - karger.com
Background: Recent studies have identified the combination of vancomycin with piperacillin-
tazobactam (VPT) to be associated with increased nephrotoxicity. Multiple, large cohort …

Vancomycin-associated acute kidney injury: a narrative review from pathophysiology to clinical application

WC Kan, YC Chen, VC Wu, CC Shiao - International journal of molecular …, 2022 - mdpi.com
Vancomycin is the most frequently used antibiotic, accounting for up to 35% of hospitalized
patients with infection, because of its optimal bactericidal effectiveness and relatively low …

Antibiotic stewardship in the intensive care unit. An official American Thoracic Society workshop report in collaboration with the AACN, CHEST, CDC, and SCCM

RG Wunderink, A Srinivasan, PS Barie… - Annals of the …, 2020 - atsjournals.org
Intensive care units (ICUs) are an appropriate focus of antibiotic stewardship program efforts
because a large proportion of any hospital's use of parenteral antibiotics, especially broad …

[HTML][HTML] Sepsis-mediated renal dysfunction: pathophysiology, biomarkers and role of phytoconstituents in its management

A Balkrishna, S Sinha, A Kumar, V Arya… - Biomedicine & …, 2023 - Elsevier
Sepsis has evolved as an enormous health issue amongst critically ill patients. It is a major
risk factor that results in multiple organ failure and shock. Acute kidney injury (AKI) is one of …

Development and validation of a personalized model with transfer learning for acute kidney injury risk estimation using electronic health records

K Liu, X Zhang, W Chen, SL Alan, JA Kellum… - JAMA Network …, 2022 - jamanetwork.com
Importance Acute kidney injury (AKI) is a heterogeneous syndrome prevalent among
hospitalized patients. Personalized risk estimation and risk factor identification may allow …

[HTML][HTML] Acute kidney injury following the concurrent administration of antipseudomonal β-lactams and vancomycin: a network meta-analysis

I Bellos, V Karageorgiou, V Pergialiotis… - Clinical Microbiology and …, 2020 - Elsevier
Background Acute kidney injury is a major complication of vancomycin treatment, especially
when it is co-administered with other nephrotoxins. Objectives This meta-analysis aims to …

Current treatment options for acute skin and skin-structure infections

Y Golan - Clinical Infectious Diseases, 2019 - academic.oup.com
Acute bacterial skin and skin-structure infections (ABSSSIs) are a common reason for
seeking care at acute healthcare facilities, including emergency departments …