Radiotherapy (RT) is a highly effective anticancer treatment that is delivered to more than
half of all patients with cancer. In addition to the well-documented direct cytotoxic effects, RT …

Eosinophils are a prominent cell type in particular host responses such as the response to
helminth infection and allergic disease. Their effector functions have been attributed to their …

The intestine represents the largest compartment of the immune system. It is continually
exposed to antigens and immunomodulatory agents from the diet and the commensal …

Chemokines are chemotactic cytokines that control the migration and positioning of immune
cells in tissues and are critical for the function of the innate immune system. Chemokines …

Chemokines are chemo tactic cyto kines that control the migratory patterns and positioning
of all immune cells. Although chemokines were initially appreciated as important mediators …

This review will describe the structure and function of the eosinophil. The roles of several
relevant cell surface molecules and receptors will be discussed. We will also explore the …

Eosinophils are specialized myeloid cells associated with allergy and helminth infections.
Blood eosinophils demonstrate circadian cycling, as described over 80 years ago, and are …

Eosinophils in visceral adipose tissue (VAT) have been implicated in metabolic homeostasis
and the maintenance of alternatively activated macrophages (AAMs). The absence of …

The initiation of type 2 immune responses by the epithelial cell–derived cytokines IL-25, IL-
33 and TSLP has been an area of extensive research in the past decade. Such studies have …

The intestine harbors a large population of resident eosinophils, yet the function of intestinal
eosinophils has not been explored. Flow cytometry and whole-mount imaging identified …