Collagen is commonly used as a regenerative biomaterial due to its excellent
biocompatibility and wide distribution in tissues. Different kinds of hybridization or cross-links …

Large-sized bone defects are a great challenge in clinics and considerably impair the quality
of patients' daily life. Tissue engineering strategies using cells, scaffolds, and bioactive …

The sophisticated hierarchical structure that precisely combines contradictory mechanical
and biological characteristics is ideal for biomaterials, but it is challenging to achieve …

With the development of bone tissue engineering bio-scaffold materials by adding metallic
ions to improve bone healing have been extensively explored in the past decades …

In tissue engineering, bioactive materials play an important role, providing structural support,
cell regulation and establishing a suitable microenvironment to promote tissue regeneration …

The treatment of bone defects is an important problem in clinical practice. The rapid
development of bone tissue engineering (BTE) may provide a new method for bone defect …

Biopolymers-induced immune microenvironment exhibited prominent effects on bone
regeneration. Osteo-immunomodulatory responses of cellulose nanoparticles incorporated …

The regeneration of hierarchical osteochondral units is challenging due to difficulties in
inducing spatial, directional and controllable differentiation of mesenchymal stem cells …

Two major issues are currently hindering the clinical practice of titanium dental implants for
the lack of biological activities: immediate/early loading risks and peri-implantitis. To solve …

The limitations of traditional two-dimensional (2D) cultures and animal testing, when it
comes to precisely foreseeing the toxicity and clinical effectiveness of potential drug …