Metabolic rivalry: circadian homeostasis and tumorigenesis

K Kinouchi, P Sassone-Corsi - Nature Reviews Cancer, 2020 - nature.com
Circadian rhythms govern a large array of physiological and metabolic functions.
Perturbations of the daily cycle have been linked to elevated risk of developing cancer as …

Possible role of miRNAs in pheochromocytoma pathology-Signaling pathways interaction

SY Elkhawaga, A Elshafei, MA Elkady, AM Yehia… - … -Research and Practice, 2023 - Elsevier
Pheochromocytoma (PCC) is a type of neuroendocrine tumor that originates from adrenal
medulla or extra-adrenal chromaffin cells and results in the production of catecholamine …

Pheochromocytomas and abdominal paragangliomas: a practical guidance

J Calissendorff, CC Juhlin, I Bancos, H Falhammar - Cancers, 2022 - mdpi.com
Simple Summary Pheochromocytomas and abdominal paragangliomas (PPGLs) are rare.
They can be discovered incidentally by imaging with computed tomography or magnetic …

Linking metabolic reprogramming, plasticity and tumor progression

O Shuvalov, A Daks, O Fedorova, A Petukhov, N Barlev - Cancers, 2021 - mdpi.com
Simple Summary In the present review, we discuss the role of metabolic reprogramming
which occurs in malignant cells. The process of metabolic reprogramming is also known as …

Pheochromocytomas and paragangliomas: new developments with regard to classification, genetics, and cell of origin

K Koopman, J Gaal, RR de Krijger - Cancers, 2019 - mdpi.com
Pheochromocytomas (PCC) and paragangliomas (PGL) are rare neuroendocrine tumors
that arise in the adrenal medulla and in extra-adrenal locations, such as the head, neck …

Pheochromocytoma: a clinicopathologic and molecular study of 390 cases from a single center

Z Liu, J Ma, C Jimenez, M Zhang - The American Journal of …, 2021 - journals.lww.com
Pheochromocytomas are rare neuroendocrine tumors arising from chromaffin cells in the
adrenal medulla. They may occur sporadically or in the context of hereditary syndromes. All …

Exome analysis of carotid body tumor

AV Snezhkina, EN Lukyanova, DV Kalinin… - BMC medical …, 2018 - Springer
Background Carotid body tumor (CBT) is a form of head and neck paragangliomas
(HNPGLs) arising at the bifurcation of carotid arteries. Paragangliomas are commonly …

Somatic mutation profiling in head and neck paragangliomas

M Savvateeva, A Kudryavtseva… - The Journal of …, 2022 - academic.oup.com
Context Head and neck paragangliomas (HNPGLs) are rare neoplasms with a high degree
of heritability. Paragangliomas present as polygenic diseases caused by combined …

Immunohistochemistry and Mutation Analysis of SDHx Genes in Carotid Paragangliomas

AV Snezhkina, DV Kalinin, VS Pavlov… - International Journal of …, 2020 - mdpi.com
Carotid paragangliomas (CPGLs) are rare neuroendocrine tumors often associated with
mutations in SDHx genes. The immunohistochemistry of succinate dehydrogenase (SDH) …

Hif2alpha-associated pseudohypoxia promotes radioresistance in pheochromocytoma: Insights from 3d models

V Seifert, S Richter, N Bechmann, M Bachmann… - Cancers, 2021 - mdpi.com
Simple Summary Low oxygen levels (hypoxia) as well as genetic defects activating hypoxia
signaling pathways (pseudohypoxia) are known to contribute to tumorigenesis and therapy …