Biocatalytic transformation has received increasing attention in the green synthesis of
chemicals because of the diversity of enzymes, their high catalytic activities and specificities …

Peroxygenases are an emerging new class of enzymes allowing selective
oxyfunctionalisation reactions in a cofactor-independent way different from well-known P450 …

Given prominent physicochemical similarities between H2O2 and water, we report a new
strategy for promoting the peroxygenase activity of P450 enzymes by engineering their …

In general, hydrogen peroxide is a stable and relatively mild oxidant and it can be regarded
as the ultimate “green” reagent because water and oxygen are the only by-products …

Cytochromes P450 (P450 or CYP) are heme-containing enzymes that catalyze the
introduction of one atom of molecular oxygen into nonactivated C–H bonds, often in a regio …

Highlights•Peroxygenases are very promising catalysts for preparative oxyfunctionalization
chemistry.•The number of interesting applications and novel catalysts is growing …

Enzymes are the catalyst of choice for highly selective reactions, offering nature-inspired
approaches for sustainable chemical synthesis. Oxidative enzymes (eg, monooxygenases …

The search for affordable, green biocatalytic processes is a challenge for chemicals
manufacture. Redox biotransformations are potentially attractive, but they rely on unstable …

Hydrogenation reactions in biology are usually carried out by enzymes with nicotinamide
adenine dinucleotide (NAD (P) H) or flavin mononucleotide (FAMH2)/flavinadenine …

Understanding the molecular basis for controlled H2O2 activation is of fundamental
importance for peroxide-driven catalysis by metalloenzymes. In addition to O2 activation in …