Under normal conditions, inflammation is a protective and physiological response to various
harmful stimuli. However, in several chronic debilitating disorders, such as chronic kidney …

Fetuin-A is a heterodimeric plasma glycoprotein containing an A-chain of 282 amino acids
and a B-chain of 27 amino acid residues linked by a single inter-disulfide bond. It is …

Systemic inflammation in end-stage renal disease is an established risk factor for mortality
and a catalyst for other complications, which are related to a premature aging phenotype …

Background Phosphate binders are used to reduce positive phosphate balance and to lower
serum phosphate levels for people with chronic kidney disease (CKD) with the aim to …

Stenvinkel P (Division of Renal Medicine, Department of Clinical Science, Intervention and
Technology, Karolinska Institutet, Stockholm, Sweden). Chronic kidney disease: a public …

The first reports connecting uremic inflammation with a wasted and atherogenic phenotype
and poor outcome initiated in the late 1990s. Since then, about 3500 publications appear on …

Hyperphosphatemia, which is nearly universal in kidney failure, is accompanied by low
serum levels of vitamin D and hypocalcemia. Without treatment, severe secondary …

Metabolic syndrome and its components are associated with chronic kidney disease (CKD)
development. Insulin resistance (IR) plays a central role in the metabolic syndrome and is …

Hyperphosphatemia has been associated with higher mortality risk in CKD 5 patients
receiving dialysis. Here, we determined the association between the use of single and …

Inflammation is normally a protective and physiological response to harmful stimuli, but
typically becomes an uncontrolled, maladaptive, and persistent process in patients with end …