Block copolymer micelles in nanomedicine applications
Polymeric micelles are demonstrating high potential as nanomedicines capable of
controlling the distribution and function of loaded bioactive agents in the body, effectively …
controlling the distribution and function of loaded bioactive agents in the body, effectively …
Recent progress in development of siRNA delivery vehicles for cancer therapy
Recent progress in RNA biology has broadened the scope of therapeutic targets of RNA
drugs for cancer therapy. However, RNA drugs, typically small interfering RNAs (siRNAs) …
drugs for cancer therapy. However, RNA drugs, typically small interfering RNAs (siRNAs) …
Cyclic ruthenium-peptide conjugates as integrin-targeting phototherapeutic prodrugs for the treatment of brain tumors
To investigate the potential of tumor-targeting photoactivated chemotherapy, a chiral
ruthenium-based anticancer warhead, Λ/Δ-[Ru (Ph2phen) 2 (OH2) 2] 2+, was conjugated to …
ruthenium-based anticancer warhead, Λ/Δ-[Ru (Ph2phen) 2 (OH2) 2] 2+, was conjugated to …
Nanoengineered neutrophils as a cellular sonosensitizer for visual sonodynamic therapy of malignant tumors
L Sun, J Zhou, T Luo, J Wang, L Kang… - Advanced …, 2022 - Wiley Online Library
The rapid evolution of cell‐based theranostics has attracted extensive attention due to their
unique advantages in biomedical applications. However, the inherent functions of cells …
unique advantages in biomedical applications. However, the inherent functions of cells …
Gold nanoclusters for biomedical applications: toward in vivo studies
E Porret, X Le Guével, JL Coll - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
In parallel with the rapidly growing and widespread use of nanomedicine in the clinic, we
are also witnessing the development of so-called theranostic agents that combine diagnostic …
are also witnessing the development of so-called theranostic agents that combine diagnostic …
Application of near-infrared dyes for tumor imaging, photothermal, and photodynamic therapies
ABSTRACT Near‐infrared (NIR) dyes, small organic molecules that function in the NIR
region, have received increasing attention in recent years as diagnostic and therapeutic …
region, have received increasing attention in recent years as diagnostic and therapeutic …
Advancement in integrin facilitated drug delivery
D Arosio, C Casagrande - Advanced Drug Delivery Reviews, 2016 - Elsevier
The research of integrin-targeted anticancer agents has recorded important advancements
in ingenious design of delivery systems, based either on the prodrug approach, or on …
in ingenious design of delivery systems, based either on the prodrug approach, or on …
Ultrasound molecular imaging of tumor angiogenesis with an integrin targeted microbubble contrast agent
Rationale and Objectives: Ultrasound molecular imaging is an emerging technique for
sensitive detection of intravascular targets. Molecular imaging of angiogenesis has strong …
sensitive detection of intravascular targets. Molecular imaging of angiogenesis has strong …
Targeted polymeric micelles for siRNA treatment of experimental cancer by intravenous injection
Small interfering ribonucleic acid (siRNA) cancer therapies administered by intravenous
injection require a delivery system for transport from the bloodstream into the cytoplasm of …
injection require a delivery system for transport from the bloodstream into the cytoplasm of …
Increased Tumor Penetration of Single-Domain Antibody–Drug Conjugates Improves In Vivo Efficacy in Prostate Cancer Models
Targeted delivery of chemotherapeutics aims to increase efficacy and lower toxicity by
concentrating drugs at the site-of-action, a method embodied by the seven current FDA …
concentrating drugs at the site-of-action, a method embodied by the seven current FDA …