Cyclodextrin (CD), a class of cyclic oligosaccharides with an external hydrophilic surface
and a central hydrophobic cavity is recognized as a promising pharmaceutical excipient due …

Drug permeation across the cornea remains a major challenge due to its unique and
complex anatomy and physiology. Static barriers such as the different layers of the cornea …

Poor bioavailability of eye drops is a well-known issue, which can be improved by
increasing the residence time on the eye surface and the penetration of the active …

The objective of the current study was to fabricate a thermosensitive in situ gelling system for
the ocular delivery of carvedilol-loaded spanlastics (CRV-SPLs). In situ gel formulations …

The incidence of ocular pathologies is constantly increasing, as is the interest of the
researchers in developing new strategies to ameliorate the treatment of these conditions …

Nowadays, hyaluronic acid (HA) eye drops are widely used to combat ophthalmic dry eye
disease (DED). Till the date, almost all commercialized HA eye drops are single-ingredient …

Nepafenac is a highly effective NSAID used for treating postoperative ocular inflammation
and pain after cataract surgery and its advantage over conventional topical NSAIDs has …

Dexamethasone (DXM) is a commonly used corticosteroid in the treatment of ocular
inflammatory conditions that affect more and more people. The aim of this study was to …

The hydrocortisone-type corticosteroid (HTC) group includes valuable active pharmaceutical
ingredients (APIs) such as hydrocortisone, hydrocortisone acetate, cortisone acetate …

Purpose Fungal ocular infection is challenging to treat and remains significant cause of
blindness globally. The complex structure and physiology of the eye limits the drug targeting …