Marine fungi: A source of potential anticancer compounds
Metabolites from marine fungi have hogged the limelight in drug discovery because of their
promise as therapeutic agents. A number of metabolites related to marine fungi have been …
promise as therapeutic agents. A number of metabolites related to marine fungi have been …
Natural products and synthetic analogues against HIV: A perspective to develop new potential anti-HIV drugs
The human immunodeficiency virus (HIV) is responsible for acquired immune deficiency
syndrome (AIDS), one of the major pandemic diseases. Highly active antiretroviral therapy …
syndrome (AIDS), one of the major pandemic diseases. Highly active antiretroviral therapy …
Nanodiamonds: the intersection of nanotechnology, drug development, and personalized medicine
The implementation of nanomedicine in cellular, preclinical, and clinical studies has led to
exciting advances ranging from fundamental to translational, particularly in the field of …
exciting advances ranging from fundamental to translational, particularly in the field of …
Immunometabolism and HIV-1 pathogenesis: food for thought
A Saez-Cirion, I Sereti - Nature reviews immunology, 2021 - nature.com
Antiretroviral therapies efficiently block HIV-1 replication but need to be maintained for life.
Moreover, chronic inflammation is a hallmark of HIV-1 infection that persists despite …
Moreover, chronic inflammation is a hallmark of HIV-1 infection that persists despite …
Environmental fate and ecotoxicological effects of antiretrovirals: a current global status and future perspectives
The therapeutic efficacy of antiretroviral drugs as well as challenges and side effects against
the human immunodeficiency virus is well documented and reviewed. Evidence is available …
the human immunodeficiency virus is well documented and reviewed. Evidence is available …
Adeno-associated virus delivery of anti-HIV monoclonal antibodies can drive long-term virologic suppression
JM Martinez-Navio, SP Fuchs, SN Pantry, WA Lauer… - Immunity, 2019 - cell.com
Long-term delivery of anti-HIV monoclonal antibodies (mAbs) using adeno-associated virus
(AAV) vectors holds promise for the prevention and treatment of HIV infection. We describe a …
(AAV) vectors holds promise for the prevention and treatment of HIV infection. We describe a …
Strategies to eradicate HIV from infected patients: elimination of latent provirus reservoirs
I Sadowski, FB Hashemi - Cellular and Molecular Life Sciences, 2019 - Springer
Abstract 35 years since identification of HIV as the causative agent of AIDS, and 35 million
deaths associated with this disease, significant effort is now directed towards the …
deaths associated with this disease, significant effort is now directed towards the …
[HTML][HTML] Impact of antiretroviral therapy on lipid metabolism of human immunodeficiency virus-infected patients: Old and new drugs
J da Cunha, LMF Maselli, ACB Stern… - World journal of …, 2015 - ncbi.nlm.nih.gov
For human immunodeficiency virus (HIV)-infected patients, the 1990s were marked by the
introduction of highly active antiretroviral therapy (HAART) representing a new perspective …
introduction of highly active antiretroviral therapy (HAART) representing a new perspective …
Stimulating the RIG-I pathway to kill cells in the latent HIV reservoir following viral reactivation
P Li, P Kaiser, HW Lampiris, P Kim, SA Yukl… - Nature medicine, 2016 - nature.com
The persistence of latent HIV proviruses in long-lived CD4+ T cells despite antiretroviral
therapy (ART),, is a major obstacle to viral eradication,,. Because current candidate latency …
therapy (ART),, is a major obstacle to viral eradication,,. Because current candidate latency …
Novel assays for measurement of total cell-associated HIV-1 DNA and RNA
Although a number of PCR-based quantitative assays for measuring HIV-1 persistence
during suppressive antiretroviral therapy (ART) have been reported, a simple, sensitive …
during suppressive antiretroviral therapy (ART) have been reported, a simple, sensitive …