Dynamics of B cells in germinal centres
NS De Silva, U Klein - Nature reviews immunology, 2015 - nature.com
Humoral immunity depends on the germinal centre (GC) reaction during which somatically
mutated high-affinity memory B cells and plasma cells are generated. Recent studies have …
mutated high-affinity memory B cells and plasma cells are generated. Recent studies have …
Role of host and pathogen-derived microRNAs in immune regulation during infectious and inflammatory diseases
MicroRNAs (miRNAs, miRs) are short, endogenously initiated, non-coding RNAs that bind to
target mRNAs, leading to the degradation or translational suppression of respective mRNAs …
target mRNAs, leading to the degradation or translational suppression of respective mRNAs …
MicroRNAs in B-cell lymphomas: how a complex biology gets more complex
K Musilová, M Mráz - Leukemia, 2015 - nature.com
MicroRNAs (miRNAs) represent important regulators of gene expression besides
transcriptional control. miRNA regulation can be involved in the cell developmental fate …
transcriptional control. miRNA regulation can be involved in the cell developmental fate …
MicroRNAs: Essential players in the regulation of inflammation
Regulation of inflammatory responses is ensured by coordinated control of gene expression
in participating immune system and tissue cells. One group of gene expression regulators …
in participating immune system and tissue cells. One group of gene expression regulators …
The RNA-binding protein HuR is essential for the B cell antibody response
Post-transcriptional regulation of mRNA by the RNA-binding protein HuR (encoded by
Elavl1) is required in B cells for the germinal center reaction and for the production of class …
Elavl1) is required in B cells for the germinal center reaction and for the production of class …
Clinical significance of miRNAs in autoimmunity
MicroRNAs (miRNAs) are evolutionally conserved, single-stranded RNAs that regulate gene
expression at the posttranscriptional level by disrupting translation. MiRNAs are key players …
expression at the posttranscriptional level by disrupting translation. MiRNAs are key players …
Altered lymphopoiesis and immunodeficiency in miR-142 null mice
MicroRNAs (miRNAs) are a class of powerful posttranscriptional regulators implicated in the
control of diverse biological processes, including regulation of hematopoiesis and the …
control of diverse biological processes, including regulation of hematopoiesis and the …
Epigenetics of peripheral B-cell differentiation and the antibody response
Epigenetic modifications, such as histone post-translational modifications, DNA methylation,
and alteration of gene expression by non-coding RNAs, including microRNAs (miRNAs) and …
and alteration of gene expression by non-coding RNAs, including microRNAs (miRNAs) and …
The involvement of microRNAs in modulation of innate and adaptive immunity in systemic lupus erythematosus and lupus nephritis
M Honarpisheh, P Köhler… - Journal of …, 2018 - Wiley Online Library
Noncoding RNAs (ncRNAs), including microRNAs (miRNAs), represent a family of RNA
molecules that do not translate into protein. Nevertheless, they have the ability to regulate …
molecules that do not translate into protein. Nevertheless, they have the ability to regulate …
Immunoglobulin expression and the humoral immune response is regulated by the non-canonical poly (A) polymerase TENT5C
A Bilska, M Kusio-Kobiałka, PS Krawczyk… - Nature …, 2020 - nature.com
TENT5C is a non-canonical cytoplasmic poly (A) polymerase highly expressed by activated
B cells to suppress their proliferation. Here we measure the global distribution of poly (A) tail …
B cells to suppress their proliferation. Here we measure the global distribution of poly (A) tail …