Nucleic acids have attracted widespread attention due to the simplicity with which they can
be designed to form discrete structures and programmed to perform specific functions at the …

Small-molecule and protein/antibody drugs mainly act on genome-derived proteins to exert
pharmacological effects. RNA based therapies hold the promise to expand the range of …

Programmed self-assembly of nucleic acids is a powerful approach for nano-constructions.
The assembled nanostructures have been explored for various applications. However …

RNA is becoming more important as an increasing number of functions, both regulatory and
enzymatic, are being discovered on a daily basis. As the RNA boom has just begun, most …

Antibody technology is widely used in the fields of biomedical and clinical therapies.
Nonetheless, the complex in vitro expression of recombinant proteins, long production …

Research on RNA has led to many important biological discoveries and improvement of
therapeutic technologies. From basic to applied research, many procedures employ pure …

The discovery of functional small noncoding RNAs (ncRNAs), such as microRNAs and small
interfering RNAs, in the control of human cellular processes has opened new avenues to …

Accumulating evidence has demonstrated that genome-derived noncoding RNAs (ncRNAs)
play important roles in modulating inter-individual variations observed in drug metabolism …

RNA research and therapy relies primarily on synthetic RNAs. We employed recombinant
RNA technology toward large-scale production of pre-miRNA agents in bacteria, but found …

Recent developments in the field of the messenger RNA and its advantages versus DNA
have led to a renewed interest in mRNA-based technologies. Despite its advantages, mRNA …