Gestational diabetes mellitus

HD McIntyre, P Catalano, C Zhang, G Desoye… - Nature reviews Disease …, 2019 - nature.com
Hyperglycaemia that develops during pregnancy and resolves after birth has been
recognized for over 50 years, but uniform worldwide consensus is lacking about threshold …

Comparative effectiveness of glucose-lowering drugs for type 2 diabetes: a systematic review and network meta-analysis

A Tsapas, I Avgerinos, T Karagiannis… - Annals of internal …, 2020 - acpjournals.org
Background: Several pharmacologic options for type 2 diabetes are available. Purpose: To
compare benefits and harms of glucose-lowering drugs in adults with type 2 diabetes. Data …

Metformin, macrophage dysfunction and atherosclerosis

X Feng, W Chen, X Ni, PJ Little, S Xu, L Tang… - Frontiers in …, 2021 - frontiersin.org
Metformin is one of the most widely prescribed hypoglycemic drugs and has the potential to
treat many diseases. More and more evidence shows that metformin can regulate the …

Metformin repurposing for Parkinson disease therapy: opportunities and challenges

F Agostini, A Masato, L Bubacco… - International journal of …, 2021 - mdpi.com
Parkinson disease (PD) is a severe neurodegenerative disorder that affects around 2% of
the population over 65 years old. It is characterized by the progressive loss of nigrostriatal …

Metformin-loaded polymer-based microbubbles/nanoparticles generated for the treatment of type 2 diabetes mellitus

S Cesur, ME Cam, FS Sayın, S Su, A Harker… - Langmuir, 2021 - ACS Publications
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease that is increasingly common
all over the world with a high risk of progressive hyperglycemia and high microvascular and …

Metformin inhibits IL-1β secretion via impairment of NLRP3 inflammasome in keratinocytes: implications for preventing the development of psoriasis

G Tsuji, A Hashimoto-Hachiya, VH Yen… - Cell death …, 2020 - nature.com
Psoriasis is a systemic inflammatory disease significantly associated with comorbidities
including type 2 diabetes mellitus (T2DM). Metformin is utilized as a first-line agent for …

Diabesity and antidiabetic drugs

JM Pappachan, CJ Fernandez, EC Chacko - Molecular aspects of medicine, 2019 - Elsevier
The prevalence of “diabesity”–diabetes related to obesity–has increased tremendously over
the past few decades because of the global obesity epidemic. Although bariatric surgery is …

The effect of oral diabetes medications on glycated haemoglobin (HbA1c) in Asians in primary care: a retrospective cohort real-world data study

HSA Fang, Q Gao, WY Tan, ML Lee, W Hsu, NC Tan - BMC medicine, 2022 - Springer
Background Clinical trials have demonstrated that initiating oral anti-diabetic drugs (OADs)
significantly reduce glycated hemoglobin (HbA1c) levels. However, variability in lifestyle …

Ameliorative and Antioxidative Potential of Lactobacillus plantarum-Fermented Oat (Avena sativa) and Fermented Oat Supplemented with Sidr Honey against …

HF Alharbi, R Algonaiman, H Barakat - Antioxidants, 2022 - mdpi.com
The ameliorative and antioxidative stress effects of probiotic-enriched fermented oat (FOE)
or fermented oat with honey (HFOE) extracts on streptozotocin-induced diabetes in rats were …

Effect of Lactobacillus fermentum TKSN041 on improving streptozotocin-induced type 2 diabetes in rats

X Zhou, G Shang, Q Tan, Q He, X Tan, KY Park… - Food & Function, 2021 - pubs.rsc.org
With the increasing incidence of type 2 diabetes, it is imperative to identify how to effectively
prevent or treat this disease. Studies have shown that some lactic acid bacteria can improve …