The proteins secreted by various cells (the secretomes) are a potential rich source of
biomarkers as they reflect various states of the cells at real time and at given conditions. To …

Objectives. Proteome analysis has emerged as a promising strategy to the identification of
potential biomarkers and to further confirm the importance of certain pathways in the …

We describe a protocol for easy isolation and culture of human umbilical vein endothelial
cells (HUVECs) to supply every researcher with a method that can be applied in cell biology …

The unfolded protein response (UPR) is an evolutionarily conserved mechanism that
activates both proapoptotic and survival pathways to allow eukaryotic cells to adapt to …

Abstract Glucose-regulated protein 78 (GRP78)/BiP is a multifunctional protein which plays
a major role in endoplasmic reticulum (ER) protein processing, protein quality control …

The sperm of eutherian mammals are held in a storage reservoir in the caudal segment of
the oviduct by binding to the mucosal epithelium. The reservoir serves to maintain the fertility …

Global proteomic analysis of post-mortem anterior temporal lobe samples from
schizophrenia patients and non-schizophrenia individuals was performed using stable …

There is scant knowledge regarding how cell surface lipid-anchored T-cadherin (T-cad)
transmits signals through the plasma membrane to its intracellular targets. This study aimed …

The production of biomaterials that endow significant morphogenic and microenvironmental
cues for the constitution of cell integration and regeneration remains a key challenge in the …

Background Oxidative stress (OS) is an important factor in brain aging and
neurodegenerative diseases. Certain neurons in different brain regions exhibit selective …