A clinical trial was performed to evaluate 3BNC117, a potent anti–HIV-1 antibody, in infected
individuals during suppressive antiretroviral therapy and subsequent analytical treatment …

Background: Considerable numbers of HIV-1–infected men who have sex with men (MSM)
show a relatively rapid disease progression in China; however, the cause remains elusive …

HIV superinfection describes the sequential infection of an individual with two or more
unrelated HIV strains. Intersubtype superinfection has been shown to cause a broader and …

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
developed variants escaping neutralization antibody immunity established against the …

To better understand the dynamics of HIV-specific neutralizing antibody (NAb), we examined
associations between viral genetic diversity and the NAb response against a multi-subtype …

Background HIV controllers (HICs) are a rare group of HIV-1-infected individuals able to
naturally control viral replication. Several studies have identified the occurrence of HIV dual …

The effect of serial HIV-1 infection on the development of the broadly neutralizing antibody
(bNAb) response was studied in an individual, H01-10366, with a serial HIV-1 superinfection …

A series of HIV-1 CRF01_AE/CRF07_BC recombinants were previously found to have
emerged gradually in a superinfected patient (patient LNA819). However, the extent to …

The HIV-1 epidemic was mainly driven by men who have sex with men (MSM) recently in
Beijing, China, with high genetic diversity. Novel recombinant strains were frequently …

Understanding whether the neutralizing antibody (NAb) response impacts HIV-1
superinfection and how superinfection subsequently modulates the NAb response can help …