[HTML][HTML] Perineuronal Net Microscopy: From Brain Pathology to Artificial Intelligence

M Paveliev, AA Egorchev, F Musin, N Lipachev… - International Journal of …, 2024 - mdpi.com
Perineuronal nets (PNN) are a special highly structured type of extracellular matrix
encapsulating synapses on large populations of CNS neurons. PNN undergo structural …

Electroacupuncture promotes the repair of the damaged spinal cord in mice by mediating neurocan‐perineuronal net

R Hu, K He, B Chen, Y Chen, J Zhang… - CNS Neuroscience …, 2024 - Wiley Online Library
Aims This study aimed to investigate the effect of perineuronal net (PNN) and neurocan
(NCAN) on spinal inhibitory parvalbumin interneuron (PV‐IN), and the mechanism of …

Multidimensional analysis of a social behavior identifies regression and phenotypic heterogeneity in a female mouse model for Rett syndrome

M Mykins, B Bridges, A Jo, K Krishnan - Journal of Neuroscience, 2024 - Soc Neuroscience
Regression is a key feature of neurodevelopmental disorders such as autism spectrum
disorder, Fragile X syndrome, and Rett syndrome (RTT). RTT is caused by mutations in the X …

[HTML][HTML] The role of brevican regulation in the antidepressant effects of electroacupuncture in a chronic stress rat model

C Gai, Z Guo, K Guo, S Yang, Y Zhang, H Zhu… - Journal of Traditional …, 2024 - Elsevier
Objective To investigate the mechanism of electroacupuncture (EA) for treating depression
and to explore the role of brevican in the medial prefrontal cortex (mPFC) in modulating …

Motor cortex perineuronal net modulation improves motor function in a Parkinson's disease mouse model

D Benacom, C Chataing, A Prochiantz, AA Di Nardo - bioRxiv, 2024 - biorxiv.org
The 6-OHDA mouse model recapitulates midbrain dopaminergic cell loss and associated
motor deficits akin to those observed in Parkinson's disease. Emerging evidence suggests …

The Perineuronal Net Microscopy: From Brain Pathology to AI Instruments

M Paveliev, A Egorchev, M Musin… - Available at SSRN …, 2024 - papers.ssrn.com
Perineuronal nets (PNN) are a special highly structured type of extracellular matrix
encapsulating synapses on large populations of the CNS neurons. PNN undergo structural …

Developing a genetic reporter to longitudinally study perineuronal nets in vivo

F Calugi - 2023 - flore.unifi.it
Perineuronal nets (PNNs) are highly organized structures of extracellular matrix associated
with different neuronal populations throughout the CNS. In the cerebral cortex, they are …