The first paper on “inflammaging” published in 2001 paved the way for a unifying theory on
how and why aging turns out to be the main risk factor for the development of the most …

miR-21 is one of the most highly expressed members of the small non-coding microRNA
family in many mammalian cell types. Its expression is further enhanced in many diseased …

Tumor immune escape is a critical step in the malignant progression of tumors and one of
the major barriers to immunotherapy, making immunotherapy the most promising …

The role of myeloid differentiation factor 88 (MyD88) in malignant tumors is largely unknown.
Therefore, in this study, we aimed to examine the function and underlying mechanism of …

Purpose: Here we assess whether molecular subtyping identifies biological features of
tumors that correlate with survival and surgical outcomes of high-grade serous ovarian …

Pathological mechanisms underlying diabetic retinopathy are still not completely
understood. Increased understanding of potential cellular pathways responsive to …

Nuclear factor kappa B (NF-κB) is a pluripotent and crucial dimer transcription factor that
orchestrates various physiological and pathological processes, especially cell proliferation …

The influence of Toll‑like receptor (TLR) 4/myeloid differentiation factor (MyD) 88 signaling
on the invasion and metastasis of cancer cells has been previously reported. The purpose of …

Ovarian cancer (OC) is one of the most common cancers threatening women's lives around
the world. Epithelial ovarian tumors represent the most common ovarian neoplasms. Most …

Ovarian cancer is the seventh most common cancer in women and the most frequent cause
of gynaecological malignancy-related mortality in women. Currently, no standardized …