[HTML][HTML] Microglia in multiple sclerosis: Protectors turn destroyers
VW Yong - Neuron, 2022 - cell.com
Microglia are implicated in all stages of multiple sclerosis (MS). Microglia alterations are
detected by positron emission tomography in people living with MS prior to the formation of …
detected by positron emission tomography in people living with MS prior to the formation of …
A meta-analysis of pro-inflammatory cytokines in autism spectrum disorders: Effects of age, gender, and latitude
A Saghazadeh, B Ataeinia, K Keynejad… - Journal of psychiatric …, 2019 - Elsevier
Background Autism spectrum disorders (ASD) occur in 1.5% of the general population
worldwide. Studies suggest that ASD might have more costs than diabetes and attention …
worldwide. Studies suggest that ASD might have more costs than diabetes and attention …
Human CNS barrier-forming organoids with cerebrospinal fluid production
L Pellegrini, C Bonfio, J Chadwick, F Begum, M Skehel… - Science, 2020 - science.org
INTRODUCTION The choroid plexus is a secretory epithelial tissue of the central nervous
system (CNS) responsible for cerebrospinal fluid (CSF) production and functions as a barrier …
system (CNS) responsible for cerebrospinal fluid (CSF) production and functions as a barrier …
[HTML][HTML] The evolution of neurofilament light chain in multiple sclerosis
C Ferreira-Atuesta, S Reyes, G Giovanonni… - Frontiers in …, 2021 - frontiersin.org
Multiple sclerosis (MS) is an autoimmune, inflammatory neurodegenerative disease of the
central nervous system characterized by demyelination and axonal damage. Diagnosis and …
central nervous system characterized by demyelination and axonal damage. Diagnosis and …
Osteopontin in vascular disease: Friend or foe?
ZSY Lok, AN Lyle - Arteriosclerosis, thrombosis, and vascular …, 2019 - Am Heart Assoc
Inflammatory cytokines are necessary for an acute response to injury and the progressive
healing process. However, when this acute response does not resolve and becomes …
healing process. However, when this acute response does not resolve and becomes …
[HTML][HTML] Co-stimulation with IL-1β and TNF-α induces an inflammatory reactive astrocyte phenotype with neurosupportive characteristics in a human pluripotent stem …
T Hyvärinen, S Hagman, M Ristola, L Sukki, K Veijula… - Scientific reports, 2019 - nature.com
Astrocyte reactivation has been discovered to be an important contributor to several
neurological diseases. In vitro models involving human astrocytes have the potential to …
neurological diseases. In vitro models involving human astrocytes have the potential to …
[HTML][HTML] The role of osteopontin in microglia biology: current concepts and future perspectives
The innate immune landscape of the central nervous system (CNS), including the brain and
the retina, consists of different myeloid cell populations with distinct tasks to fulfill. Whereas …
the retina, consists of different myeloid cell populations with distinct tasks to fulfill. Whereas …
Inflammation in neurological disorders: the thin boundary between brain and periphery
C Cervellati, A Trentini, A Pecorelli… - Antioxidants & Redox …, 2020 - liebertpub.com
Significance: Accumulating evidence suggests that inflammation is a major contributor in the
pathogenesis of several highly prevalent, but also rare, neurological diseases. In particular …
pathogenesis of several highly prevalent, but also rare, neurological diseases. In particular …
CSF and blood biomarkers in neuroinflammatory and neurodegenerative diseases: implications for treatment
Neuroinflammatory and neurodegenerative diseases are characterized by the interplay of a
number of molecular pathways that can be assessed through biofluids, especially …
number of molecular pathways that can be assessed through biofluids, especially …
Emerging imaging and liquid biomarkers in multiple sclerosis
The advent of highly effective disease modifying therapy has transformed the landscape of
multiple sclerosis (MS) care over the last two decades. However, there remains a critical …
multiple sclerosis (MS) care over the last two decades. However, there remains a critical …