Nanoparticle-based therapeutics and diagnostics are commonly referred to as
nanomedicine and may significantly impact the future of healthcare. However, the clinical …

The interest in functional supramolecular systems for the design of innovative materials and
technologies, able to fundamentally change the world, is growing at a high pace. The huge …

Gold nanomaterials have attracted considerable interest as vehicles for intracellular drug
delivery. In our study, we synthesized three different shapes of methylpolyethylene glycol …

Genome editing through the delivery of CRISPR/Cas9-ribonucleoprotein (Cas9-RNP)
reduces unwanted gene targeting and avoids integrational mutagenesis that can occur …

Targeted drug delivery in cancer typically focuses on maximising the endocytosis of drugs
into the diseased cells. However, there has been less focus on exploiting the differences in …

Growth in production of manufactured goods and the use of nanomaterials in consumer
products has mounted in the past few decades. Nanotoxicology or toxicity assessment of …

Correlation of the surface physicochemical properties of nanoparticles with their interactions
with biosystems provides key foundational data for nanomedicine. We report here the …

Nanoparticulate drug/gene carriers have gained much attention in the past decades
because of their versatile and tunable properties. However, efficacy of the therapeutic …

DOI: 10.1002/adma. 201400866 properties as that of a polypeptide comprising of several
GSH molecules, and this class of materials have been shown to have good biocompatibility …

Size, shape, and protein corona play a key role in cellular uptake and removal mechanisms
of gold nanoparticles (Au NPs). The 15 nm nanoparticles (NP1), the 45 nm nanoparticles …