The 17q23 amplicon and breast cancer
CS Sinclair, M Rowley, A Naderi, FJ Couch - Breast cancer research and …, 2003 - Springer
A novel region of amplification in breast tumors was recently identified on chromosome
17q23. Extensive mapping of the amplicon by Southern blotting and fluorescence in situ …
17q23. Extensive mapping of the amplicon by Southern blotting and fluorescence in situ …
MicroRNAs (miRNAs) as biomarker (s) for prognosis and diagnosis of gastrointestinal (GI) cancers
MA Macha, P Seshacharyulu… - Current …, 2014 - ingentaconnect.com
Gastrointestinal (GI) cancers remain one of the most common malignancies and are the
second common cause of cancer deaths worldwide. The limited effectiveness of therapy for …
second common cause of cancer deaths worldwide. The limited effectiveness of therapy for …
[HTML][HTML] SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas
Lineage-survival oncogenes are activated by somatic DNA alterations in cancers arising
from the cell lineages in which these genes play a role in normal development,. Here we …
from the cell lineages in which these genes play a role in normal development,. Here we …
Identification of a Novel Gene, GASC1, within an Amplicon at 9p23–24 Frequently Detected in Esophageal Cancer Cell Lines
In a recent study, we identified frequent amplification of DNA copy number at chromosome
9p23–24 in cell lines derived from esophageal squamous cell carcinomas (ESCs), using …
9p23–24 in cell lines derived from esophageal squamous cell carcinomas (ESCs), using …
Overexpression of EIF5A2 promotes colorectal carcinoma cell aggressiveness by upregulating MTA1 through C-myc to induce epithelial–mesenchymaltransition
W Zhu, MY Cai, ZT Tong, SS Dong, SJ Mai, YJ Liao… - Gut, 2012 - gut.bmj.com
Background and Aims The authors have previously isolated a putative oncogene, eukaryotic
initiation factor 5A2 (EIF5A2) from 3q26. In this study, EIF5A2 was characterised for its role in …
initiation factor 5A2 (EIF5A2) from 3q26. In this study, EIF5A2 was characterised for its role in …
[PDF][PDF] Overexpression of eukaryotic initiation factor 5A2 enhances cell motility and promotes tumor metastasis in hepatocellular carcinoma
A high incidence of tumor recurrence and metastasis has been reported in hepatocellular
carcinoma (HCC) patients; however, the underlying molecular mechanisms are largely …
carcinoma (HCC) patients; however, the underlying molecular mechanisms are largely …
Identification of cIAP1 As a Candidate Target Gene within an Amplicon at 11q22 in Esophageal Squamous Cell Carcinomas
Amplification of chromosomal DNA is thought to be one of the mechanisms that activate
cancer-related genes in tumors. In a recent study, we identified high copy-number …
cancer-related genes in tumors. In a recent study, we identified high copy-number …
[图书][B] Molecular biology of cancer
F Macdonald, C Ford, A Casson - 2004 - taylorfrancis.com
Molecular Biology of Cancer has been extensively revised and covers heredity cancer,
microarray technology and increased study of childhood cancers. It continues to provide a …
microarray technology and increased study of childhood cancers. It continues to provide a …
Isolation of a novel candidate oncogene within a frequently amplified region at 3q26 in ovarian cancer
XY Guan, JST Sham, TCM Tang, Y Fang, KK Huo… - Cancer research, 2001 - AACR
Abstract Amplification of 3q25-q26 was one of the most frequent chromosomal alterations in
human ovarian carcinoma. A chromosome microdissection-hybrid selection method was …
human ovarian carcinoma. A chromosome microdissection-hybrid selection method was …
Genetic and histologic studies of somatomammotropic pituitary tumors in patients with the “complex of spotty skin pigmentation, myxomas, endocrine overactivity and …
Carney complex (CNC) is a familial multiple neoplasia and lentiginosis syndrome with
features overlapping those of McCune-Albright syndrome (MAS) and other multiple …
features overlapping those of McCune-Albright syndrome (MAS) and other multiple …