Prostate cancer screening and the associated controversy

W Tabayoyong, R Abouassaly - Surgical Clinics, 2015 - surgical.theclinics.com
Prostate cancer is the most common cancer diagnosed in males in the United States. In
2014, the American Cancer Society estimated that 233,000 patients would be diagnosed …

Intermediate and longer-term outcomes from a prospective active-surveillance program for favorable-risk prostate cancer

JJ Tosoian, M Mamawala, JI Epstein… - Journal of Clinical …, 2015 - ascopubs.org
Purpose To assess long-term outcomes of men with favorable-risk prostate cancer in a
prospective, active-surveillance program. Methods Curative intervention was recommended …

Prostate‐specific antigen‐based prostate cancer screening: past and future

AR Alberts, IG Schoots… - International Journal of …, 2015 - Wiley Online Library
Prostate‐specific antigen‐based prostate cancer screening remains a controversial topic.
Up to now, there is worldwide consensus on the statement that the harms of population …

Prostate-specific antigen (PSA) density in the diagnostic algorithm of prostate cancer

T Nordström, O Akre, M Aly, H Grönberg… - Prostate cancer and …, 2018 - nature.com
Background Screening for prostate cancer using prostate-specific antigen (PSA) alone leads
to un-necessary biopsying and overdiagnosis. PSA density is easily accessible, but early …

Clinical utility of quantitative Gleason grading in prostate biopsies and prostatectomy specimens

G Sauter, S Steurer, TS Clauditz, T Krech, C Wittmer… - European urology, 2016 - Elsevier
Background Gleason grading is the strongest prognostic parameter in prostate cancer.
Gleason grading is categorized as Gleason≤ 6, 3+ 4, 4+ 3, 8, and 9–10, but there is …

Prostate cancer screening with prostate-specific antigen (PSA) test: a clinical practice guideline

KAO Tikkinen, P Dahm, L Lytvyn, AF Heen… - Bmj, 2018 - bmj.com
There is considerable variability among men's values and preferences regarding prostate
cancer screening. Men who place a high value in avoiding complications from biopsies and …

Comparison between the four-kallikrein panel and prostate health index for predicting prostate cancer

T Nordström, A Vickers, M Assel, H Lilja, H Grönberg… - European urology, 2015 - Elsevier
Background The four-kallikrein panel and the Prostate Health Index (PHI) have been shown
to improve prediction of prostate cancer (PCa) compared with prostate-specific antigen …

[HTML][HTML] Association of multiparametric MRI quantitative imaging features with prostate cancer gene expression in MRI-targeted prostate biopsies

R Stoyanova, A Pollack, M Takhar, C Lynne, N Parra… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Standard clinicopathological variables are inadequate for optimal management of prostate
cancer patients. While genomic classifiers have improved patient risk classification, the …

Risk score predicts high‐grade prostate cancer in DNA‐methylation positive, histopathologically negative biopsies

L Van Neste, AW Partin, GD Stewart, JI Epstein… - The …, 2016 - Wiley Online Library
BACKGROUND Prostate cancer (PCa) diagnosis is challenging because efforts for effective,
timely treatment of men with significant cancer typically result in over‐diagnosis and repeat …

Economic analysis of prostate-specific antigen screening and selective treatment strategies

JA Roth, R Gulati, JL Gore, MR Cooperberg… - JAMA …, 2016 - jamanetwork.com
Importance Prostate-specific antigen (PSA) screening for prostate cancer is controversial.
Experts have suggested more personalized or more conservative strategies to improve …