Autophagy in major human diseases
Autophagy is a core molecular pathway for the preservation of cellular and organismal
homeostasis. Pharmacological and genetic interventions impairing autophagy responses …
homeostasis. Pharmacological and genetic interventions impairing autophagy responses …
Liquid–liquid phase separation drives cellular function and dysfunction in cancer
S Mehta, J Zhang - Nature Reviews Cancer, 2022 - nature.com
Cancer is a disease of uncontrollably reproducing cells. It is governed by biochemical
pathways that have escaped the regulatory bounds of normal homeostatic balance. This …
pathways that have escaped the regulatory bounds of normal homeostatic balance. This …
Targeting apoptosis in cancer therapy
BA Carneiro, WS El-Deiry - Nature reviews Clinical oncology, 2020 - nature.com
For over three decades, a mainstay and goal of clinical oncology has been the development
of therapies promoting the effective elimination of cancer cells by apoptosis. This …
of therapies promoting the effective elimination of cancer cells by apoptosis. This …
Autophagy and autophagy-related proteins in cancer
X Li, S He, B Ma - Molecular cancer, 2020 - Springer
Autophagy, as a type II programmed cell death, plays crucial roles with autophagy-related
(ATG) proteins in cancer. Up to now, the dual role of autophagy both in cancer progression …
(ATG) proteins in cancer. Up to now, the dual role of autophagy both in cancer progression …
Potential mechanisms of quercetin in cancer prevention: focus on cellular and molecular targets
Over the past few years, the cancer-related disease has had a high mortality rate and
incidence worldwide, despite clinical advances in cancer treatment. The drugs used for …
incidence worldwide, despite clinical advances in cancer treatment. The drugs used for …
Nanoagent‐promoted mild‐temperature photothermal therapy for cancer treatment
G Gao, X Sun, G Liang - Advanced Functional Materials, 2021 - Wiley Online Library
Photothermal therapy (PTT), which utilizes near‐infrared light‐absorbing agents to ablate
tumor, has emerged as a highly promising anticancer strategy and received intensive …
tumor, has emerged as a highly promising anticancer strategy and received intensive …
Low temperature photothermal therapy: Advances and perspectives
K Yang, S Zhao, B Li, B Wang, M Lan, X Song - Coordination Chemistry …, 2022 - Elsevier
Photothermal therapy (PTT) has received increasing attention due to its high selectivity, non-
invasiveness, negligible drug resistance, oxygen independence, and minimal side effects. In …
invasiveness, negligible drug resistance, oxygen independence, and minimal side effects. In …
[HTML][HTML] Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects
SM Tang, XT Deng, J Zhou, QP Li, XX Ge… - Biomedicine & …, 2020 - Elsevier
Quercetin is a kind of flavonoid compounds that comes from nature and is widely existed in
the daily diet. Previous studies have found that quercetin has many effects such as anti …
the daily diet. Previous studies have found that quercetin has many effects such as anti …
The roles of autophagy in cancer
CW Yun, SH Lee - International journal of molecular sciences, 2018 - mdpi.com
Autophagy is an intracellular degradative process that occurs under several stressful
conditions, including organelle damage, the presence of abnormal proteins, and nutrient …
conditions, including organelle damage, the presence of abnormal proteins, and nutrient …
Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein
E Dai, L Han, J Liu, Y Xie, G Kroemer, DJ Klionsky… - Autophagy, 2020 - Taylor & Francis
ABSTRACT KRAS is the most frequently mutated oncogene in human neoplasia. Despite a
large investment to understand the effects of KRAS mutation in cancer cells, the direct effects …
large investment to understand the effects of KRAS mutation in cancer cells, the direct effects …