Regenerative stem cell therapy for neurodegenerative diseases: an overview

F Sivandzade, L Cucullo - International journal of molecular sciences, 2021 - mdpi.com
Neurodegenerative diseases resulting from the progressive loss of structure and/or function
of neurons contribute to different paralysis degrees and loss of cognition and sensation. The …

Directional induction of neural stem cells, a new therapy for neurodegenerative diseases and ischemic stroke

L Nie, D Yao, S Chen, J Wang, C Pan, D Wu… - Cell Death …, 2023 - nature.com
Due to the limited capacity of the adult mammalian brain to self-repair and regenerate,
neurological diseases, especially neurodegenerative disorders and stroke, characterized by …

Exosomes‐loaded Electroconductive hydrogel synergistically promotes tissue repair after spinal cord injury via Immunoregulation and enhancement of myelinated …

L Fan, C Liu, X Chen, L Zheng, Y Zou, H Wen… - Advanced …, 2022 - Wiley Online Library
Electroconductive hydrogels are very attractive candidates for accelerated spinal cord injury
(SCI) repair because they match the electrical and mechanical properties of neural tissue …

Deep learning-based predictive identification of neural stem cell differentiation

Y Zhu, R Huang, Z Wu, S Song, L Cheng… - Nature communications, 2021 - nature.com
The differentiation of neural stem cells (NSCs) into neurons is proposed to be critical in
devising potential cell-based therapeutic strategies for central nervous system (CNS) …

Immunomodulatory layered double hydroxide nanoparticles enable neurogenesis by targeting transforming growth factor-β receptor 2

R Zhu, X Zhu, Y Zhu, Z Wang, X He, Z Wu, L Xue… - ACS …, 2021 - ACS Publications
Immune microenvironment amelioration and reconstruction by functional biomaterials has
become a promising strategy for spinal cord injury (SCI) recovery. In this study, we evaluated …

MOF-encapsulated nanozyme enhanced siRNA combo: Control neural stem cell differentiation and ameliorate cognitive impairments in Alzheimer's disease model

D Yu, M Ma, Z Liu, Z Pi, X Du, J Ren, X Qu - Biomaterials, 2020 - Elsevier
Neural stem cells (NSC) transplantation is garnering considerable attention in the treatment
of neurodegenerative diseases that are associated with cognitive decline. Current methods …

Chiral nanoparticles force neural stem cell differentiation to alleviate Alzheimer's disease

B Shi, J Zhao, Z Xu, C Chen, L Xu, C Xu… - Advanced …, 2022 - Wiley Online Library
The differentiation of neural stem cells via nanomaterials has attracted attention and has
become a potential tool. However, the chirality effect in neural stem cell differentiation has …

Biocompatible iron oxide nanoring-labeled mesenchymal stem cells: an innovative magnetothermal approach for cell tracking and targeted stroke therapy

H Liu, R Sun, L Wang, X Chen, G Li, Y Cheng, G Zhai… - ACS …, 2022 - ACS Publications
Labeling stem cells with magnetic nanoparticles is a promising technique for in vivo tracking
and magnetic targeting of transplanted stem cells, which is critical for improving the …

[HTML][HTML] The effect of carbon nanotubes on osteogenic functions of adipose-derived mesenchymal stem cells in vitro and bone formation in vivo compared with that of …

Z Du, X Feng, G Cao, Z She, R Tan, KE Aifantis… - Bioactive Materials, 2021 - Elsevier
It has been well recognized that the development and use of artificial materials with high
osteogenic ability is one of the most promising means to replace bone grafting that has …

3D gelatin microsphere scaffolds promote functional recovery after spinal cord hemisection in rats

H Ke, H Yang, Y Zhao, T Li, D Xin, C Gai… - Advanced …, 2023 - Wiley Online Library
Spinal cord injury (SCI) damages signal connections and conductions, with the result that
neuronal circuits are disrupted leading to neural dysfunctions. Such injuries represent a …