[HTML][HTML] New progresses on cell surface protein HSPA5/BiP/GRP78 in cancers and COVID-19
T Li, J Fu, J Cheng, AA Elfiky, C Wei, J Fu - Frontiers in Immunology, 2023 - frontiersin.org
Heat-shock-protein family A (Hsp70) member 5 (HSPA5), aliases GRP78 or BiP, is a protein
encoded with 654 amino acids by the HSPA5 gene located on human chromosome 9q33. 3 …
encoded with 654 amino acids by the HSPA5 gene located on human chromosome 9q33. 3 …
[HTML][HTML] Immunomodulatory role of metalloproteinase ADAM17 in tumor development
K Wang, Z Xuan, X Liu, M Zheng, C Yang… - Frontiers in …, 2022 - frontiersin.org
ADAM17 is a member of the a disintegrin and metalloproteinase (ADAM) family of
transmembrane proteases involved in the shedding of some cell membrane proteins and …
transmembrane proteases involved in the shedding of some cell membrane proteins and …
[HTML][HTML] P38 MAPK activated ADAM17 mediates ACE2 shedding and promotes cardiac remodeling and heart failure after myocardial infarction
Q Chen, Y Li, B Bie, B Zhao, Y Zhang, S Fang… - Cell Communication and …, 2023 - Springer
Background Heart failure (HF) after myocardial infarction (MI) is a prevalent disease with a
poor prognosis. Relieving pathological cardiac remodeling and preserving cardiac function …
poor prognosis. Relieving pathological cardiac remodeling and preserving cardiac function …
[HTML][HTML] Effect of DPP4/CD26 expression on SARS‑CoV‑2 susceptibility, immune response, adenosine (derivatives m62A and CD) regulations on patients with …
J Du, J Fu, W Zhang, L Zhang… - International …, 2023 - spandidos-publications.com
The worldwide COVID‑19 pandemic was brought on by a new coronavirus (SARS Cov‑2). A
marker/receptor called Dipeptidyl peptidase 4/CD26 (DPP4/CD26) may be crucial in …
marker/receptor called Dipeptidyl peptidase 4/CD26 (DPP4/CD26) may be crucial in …
[HTML][HTML] Antiviral potential of small molecules cordycepin, thymoquinone, and N6, N6-dimethyladenosine targeting SARS-CoV-2 entry protein ADAM17
J He, S Liu, Q Tan, Z Liu, J Fu, T Li, C Wei, X Liu, Z Mei… - Molecules, 2022 - mdpi.com
COVID-19 is an acute respiratory disease caused by SARS-CoV-2 that has spawned a
worldwide pandemic. ADAM17 is a sheddase associated with the modulation of the receptor …
worldwide pandemic. ADAM17 is a sheddase associated with the modulation of the receptor …
[HTML][HTML] BTG2 and SerpinB5, a novel gene pair to evaluate the prognosis of lung adenocarcinoma
W Yang, C Wei, J Cheng, R Ding, Y Li, Y Wang… - Frontiers in …, 2023 - frontiersin.org
Introduction Lung adenocarcinoma (LUAD), as the most frequent pathological subtype of
non− small cell lung cancer, is often characterized by poor prognosis and low 5-year …
non− small cell lung cancer, is often characterized by poor prognosis and low 5-year …
[HTML][HTML] Impact of BSG/CD147 gene expression on diagnostic, prognostic and therapeutic strategies towards malignant cancers and possible susceptibility to SARS …
J Fu, B Song, J Du, S Liu, J He, T Xiao, B Zhou… - Molecular Biology …, 2023 - Springer
Background BSG (CD147) is a member of the immunoglobulin superfamily that shows roles
for potential prognostics and therapeutics for metastatic cancers and SARS-CoV-2 invasion …
for potential prognostics and therapeutics for metastatic cancers and SARS-CoV-2 invasion …
[HTML][HTML] Impact of TMPRSS2 Expression, Mutation Prognostics, and Small Molecule (CD, AD, TQ, and TQFL12) Inhibition on Pan-Cancer Tumors and Susceptibility to …
J Fu, S Liu, Q Tan, Z Liu, J Qian, T Li, J Du, B Song… - Molecules, 2022 - mdpi.com
As a cellular protease, transmembrane serine protease 2 (TMPRSS2) plays roles in various
physiological and pathological processes, including cancer and viral entry, such as severe …
physiological and pathological processes, including cancer and viral entry, such as severe …
[HTML][HTML] CTSL, a prognostic marker of breast cancer, that promotes proliferation, migration, and invasion in cells in triple-negative breast cancer
L Zhang, Y Zhao, J Yang, Y Zhu, T Li, X Liu… - Frontiers in …, 2023 - frontiersin.org
Introduction In the world, the incidence of breast cancer has surpassed that of lung cancer,
and it has become the first malignant tumor among women. Triple-negative breast cancer …
and it has become the first malignant tumor among women. Triple-negative breast cancer …
New insights into mechanisms of endothelial insulin resistance in type 2 diabetes
J Padilla, C Manrique-Acevedo… - American Journal of …, 2022 - journals.physiology.org
Insulin resistance in the vasculature is a hallmark of type 2 diabetes (T2D), and blunting of
insulin-induced vasodilation is its primary consequence. Individuals with T2D exhibit a …
insulin-induced vasodilation is its primary consequence. Individuals with T2D exhibit a …