血管内皮细胞和内皮细胞释放的活性因子是调控血管舒张功能的重要因素. 糖尿病是慢性心血管
疾病的高危因素之一. 目前认为高糖和糖尿病引起的内皮细胞功能障碍是造成血管功能改变 …

A number of anti-angiogenesis drugs have been FDA-approved and are being used in
cancer treatment, and a number of other agents are in different stages of clinical …

Preeclampsia, a systemic vascular disorder characterized by new-onset hypertension and
proteinuria after 20 weeks of gestation, is the leading cause of maternal and perinatal …

Purpose The present study aimed to investigate the effects of low-intensity resistance
training with blood flow restriction (BFR resistance training) on vascular endothelial function …

Vascular endothelial growth factor (VEGF) is a highly specific mitogen for vascular
endothelial cells. Five VEGF isoforms are generated as a result of alternative splicing from a …

The skin interstitium sequesters excess Na+ and Cl–in salt-sensitive hypertension.
Mononuclear phagocyte system (MPS) cells are recruited to the skin, sense the hypertonic …

Background Hypertension (HTN) is an on-target effect of the vascular endothelial growth
factor pathway inhibitor, sunitinib. We evaluated the association of sunitinib-induced HTN …

Advances in understanding the role of vascular endothelial growth factor (VEGF) in normal
physiology are giving insight into the basis of adverse effects attributed to the use of VEGF …

Nitric oxide (NO) plays a critical role in vascular endothelial growth factor (VEGF)-induced
angiogenesis and vascular hyperpermeability. However, the relative contribution of different …

Experimental work during the past 15 years has demonstrated that endothelial cells in the
heart play an obligatory role in regulating and maintaining cardiac function, in particular, at …