Multifactorial diseases of the heart, kidneys, lungs, and liver and incident cancer: epidemiology and shared mechanisms

C Shi, S de Wit, E Učambarlić… - Cancers, 2023 - mdpi.com
Simple Summary Multifactorial diseases are caused by a combination of genetic and
environmental factors and various risk factors that accumulate with age. Cardiovascular …

Priorities in Cardio-Oncology Basic and Translational Science: GCOS 2023 Symposium Proceedings: JACC: CardioOncology State-of-the-Art Review

FN Salloum, CG Tocchetti, P Ameri, H Ardehali… - Cardio Oncology, 2023 - jacc.org
Despite improvements in cancer survival, cancer therapy–related cardiovascular toxicity has
risen to become a prominent clinical challenge. This has led to the growth of the burgeoning …

Mechanisms shared between cancer, heart failure, and targeted anti-cancer therapies

S de Wit, C Glen, RA de Boer… - Cardiovascular …, 2022 - academic.oup.com
Heart failure (HF) and cancer are the leading causes of death worldwide and accumulating
evidence demonstrates that HF and cancer affect one another in a bidirectional way …

Bidirectional relationship between cancer and heart failure: insights on circulating biomarkers

M Chianca, G Panichella, I Fabiani… - Frontiers in …, 2022 - frontiersin.org
Cancer and heart failure are the two leading causes of death in developed countries. These
two apparently distinct clinical entities share similar risk factors, symptoms, and …

Heart failure-induced microbial dysbiosis contributes to colonic tumour formation in mice

S de Wit, L Geerlings, C Shi, J Dronkers… - Cardiovascular …, 2024 - academic.oup.com
Aims Heart failure (HF) and cancer are the leading causes of death worldwide.
Epidemiological studies revealed that HF patients are prone to develop cancer. Preclinical …

Small extracellular vesicles from infarcted and failing heart accelerate tumor growth

T Caller, I Rotem, O Shaihov-Teper, D Lendengolts… - Circulation, 2024 - Am Heart Assoc
BACKGROUND: Myocardial infarction (MI) and heart failure are associated with an
increased incidence of cancer. However, the mechanism is complex and unclear. Here, we …

Temporal trends in the incidence of malignancy in heart failure: a nationwide Danish study

J Bruhn, M Malmborg, CH Garred, P Ravn… - European heart …, 2023 - academic.oup.com
Aims Cancer and heart failure (HF) share risk factors, pathophysiological mechanisms, and
possibly genetics. Improved HF survival may increase the risk of cancer due to a competing …

Cancer is a comorbidity of heart failure

P Ameri, E Bertero, WC Meijers - European heart journal, 2023 - academic.oup.com
In the last 5 years, growing attention has been paid to the occurrence of cancer in
individuals who already have heart failure (HF). 1 The issue of cancer in HF was further …

Clonal hematopoiesis in myeloproliferative neoplasms confers a predisposition to both thrombosis and cancer

T Barbui, A Gavazzi, E Sciatti, MC Finazzi… - Current Hematologic …, 2023 - Springer
Abstract Purpose of Review This review focuses on vascular complications associated with
chronic myeloproliferative neoplasms (MPN) and more specifically aims to discuss the …

Air Pollution in Cardio-Oncology and Unraveling the Environmental Nexus: JACC: CardioOncology State-of-the-Art Review

W Zhu, SG Al-Kindi, S Rajagopalan, X Rao - Cardio Oncology, 2024 - jacc.org
Although recent advancements in cancer therapies have extended the lifespan of patients
with cancer, they have also introduced new challenges, including chronic health issues such …