Developmental and epileptic encephalopathies (DEEs) are a heterogeneous group of
disorders characterized by early-onset, often severe epileptic seizures and EEG …

Self-grooming is a complex innate behaviour with an evolutionarily conserved sequencing
pattern and is one of the most frequently performed behavioural activities in rodents. In this …

The triggering receptor expressed on myeloid cells 2 (TREM2) is a microglial innate immune
receptor associated with a lethal form of early, progressive dementia, Nasu-Hakola disease …

Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders with a high
prevalence and impact on society. ASDs are characterized by deficits in both social behavior …

Neurotransmission is sustained by endocytosis and refilling of synaptic vesicles (SVs)
locally within the presynapse. Until recently, a consensus formed that after exocytosis, SVs …

Autism spectrum disorder (ASD) is thought to result from deviation from normal development
of neural circuits and synaptic function. Many genes with mutation in ASD patients have …

Autism spectrum disorders (ASD) and epilepsy are common neurological diseases of
childhood, with an estimated incidence of approximately 0.5–1% of the worldwide …

Intellectual disability (ID) and autism spectrum disorder (ASD) are the most common
developmental disorders present in humans. Combined, they affect between 3 and 5% of …

Animal models provide preclinical tools to investigate the causal role of genetic mutations
and environmental factors in the etiology of autism spectrum disorder (ASD). Knockout and …

Autism is a behaviourally defined disorder including attenuated or abnormal social
interaction and communication, as well as aberrant repetitive behaviour, with symptoms …