[HTML][HTML] Engineering nanoparticle toolkits for mRNA delivery

B Sun, W Wu, EA Narasipura, Y Ma, C Yu… - Advanced Drug Delivery …, 2023 - Elsevier
The concept of using mRNA to produce its own medicine in situ in the body makes it an ideal
drug candidate, holding great potential to revolutionize the way we approach medicine. The …

Passive and active droplet generation with microfluidics: a review

P Zhu, L Wang - Lab on a Chip, 2017 - pubs.rsc.org
Precise and effective control of droplet generation is critical for applications of droplet
microfluidics ranging from materials synthesis to lab-on-a-chip systems. Methods for droplet …

Microfluidics for drug development: from synthesis to evaluation

Y Liu, L Sun, H Zhang, L Shang, Y Zhao - Chemical reviews, 2021 - ACS Publications
Drug development is a long process whose main content includes drug synthesis, drug
delivery, and drug evaluation. Compared with conventional drug development procedures …

PEG-PCL-based nanomedicines: A biodegradable drug delivery system and its application

P Grossen, D Witzigmann, S Sieber… - Journal of Controlled …, 2017 - Elsevier
The lack of efficient therapeutic options for many severe disorders including cancer spurs
demand for improved drug delivery technologies. Nanoscale drug delivery systems based …

[HTML][HTML] Customizing poly (lactic-co-glycolic acid) particles for biomedical applications

E Swider, O Koshkina, J Tel, LJ Cruz, IJM de Vries… - Acta biomaterialia, 2018 - Elsevier
Nano-and microparticles have increasingly widespread applications in nanomedicine,
ranging from drug delivery to imaging. Poly (lactic-co-glycolic acid)(PLGA) particles are the …

Organ‐on‐a‐chip platforms: a convergence of advanced materials, cells, and microscale technologies

S Ahadian, R Civitarese, D Bannerman… - Advanced …, 2018 - Wiley Online Library
Significant advances in biomaterials, stem cell biology, and microscale technologies have
enabled the fabrication of biologically relevant tissues and organs. Such tissues and organs …

Design of functional nanoparticles by microfluidic platforms as advanced drug delivery systems for cancer therapy

A Fabozzi, F Della Sala, M di Gennaro, M Barretta… - Lab on a Chip, 2023 - pubs.rsc.org
Nanoparticle systems are functional carriers that can be used in the cancer therapy field for
the delivery of a variety of hydrophobic and/or hydrophilic drugs. Recently, the advent of …

Recent advances of controlled drug delivery using microfluidic platforms

ST Sanjay, W Zhou, M Dou, H Tavakoli, L Ma… - Advanced drug delivery …, 2018 - Elsevier
Conventional systematically-administered drugs distribute evenly throughout the body, get
degraded and excreted rapidly while crossing many biological barriers, leaving minimum …

Droplets and bubbles in microfluidic devices

SL Anna - Annual Review of Fluid Mechanics, 2016 - annualreviews.org
Precise, tunable emulsions and foams produced in microfluidic geometries have found wide
application in biochemical analysis and materials synthesis and characterization. Superb …

[HTML][HTML] The future of pharmaceutical manufacturing sciences

J Rantanen, J Khinast - Journal of pharmaceutical sciences, 2015 - Elsevier
The entire pharmaceutical sector is in an urgent need of both innovative technological
solutions and fundamental scientific work, enabling the production of highly engineered …