Polymeric micelles for the delivery of poorly soluble drugs: From nanoformulation to clinical approval
Over the last three decades, polymeric micelles have emerged as a highly promising drug
delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules …
delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules …
Polysaccharide based nanogels in the drug delivery system: Application as the carrier of pharmaceutical agents
Polysaccharide-based nanoparticles have fascinated attention as a vesicle of different
pharmaceutical agents due to their unique multi-functional groups in addition to their …
pharmaceutical agents due to their unique multi-functional groups in addition to their …
Micelles with ultralow critical micelle concentration as carriers for drug delivery
Conventional micellar carriers disassemble into free surfactants when diluted at
concentrations below the critical micelle concentration (CMC). This limits the bioavailability …
concentrations below the critical micelle concentration (CMC). This limits the bioavailability …
Micellar nanocarriers: pharmaceutical perspectives
VP Torchilin - Pharmaceutical research, 2007 - Springer
Micelles, self-assembling nanosized colloidal particles with a hydrophobic core and
hydrophilic shell are currently successfully used as pharmaceutical carriers for water …
hydrophilic shell are currently successfully used as pharmaceutical carriers for water …
Structure and design of polymeric surfactant-based drug delivery systems
VP Torchilin - Journal of controlled release, 2001 - Elsevier
The review concentrates on the use of polymeric micelles as pharmaceutical carriers.
Micellization of biologically active substances is a general phenomenon that increases the …
Micellization of biologically active substances is a general phenomenon that increases the …
Amphiphilic block copolymers for drug delivery
Amphiphilic block copolymers (ABCs) have been used extensively in pharmaceutical
applications ranging from sustained-release technologies to gene delivery. The utility of …
applications ranging from sustained-release technologies to gene delivery. The utility of …
Passive and active drug targeting: drug delivery to tumors as an example
VP Torchilin - Drug delivery, 2010 - Springer
The paradigm of using nanoparticulate pharmaceutical carriers has been well established
over the past decade, both in pharmaceutical research and in the clinical setting. Drug …
over the past decade, both in pharmaceutical research and in the clinical setting. Drug …
Biodegradable polymeric scaffolds for musculoskeletal tissue engineering
CM Agrawal, RB Ray - … Research: An Official Journal of The …, 2001 - Wiley Online Library
Biodegradable scaffolds have played an important role in a number of tissue engineering
attempts over the past decade. The goal of this review article is to provide a brief overview of …
attempts over the past decade. The goal of this review article is to provide a brief overview of …
Nano-engineering block copolymer aggregates for drug delivery
C Allen, D Maysinger, A Eisenberg - Colloids and Surfaces B: Biointerfaces, 1999 - Elsevier
This review describes the properties of block copolymer micelles which influence their
efficiency as drug delivery vehicles for hydrophobic drugs. The key performance related …
efficiency as drug delivery vehicles for hydrophobic drugs. The key performance related …
Fabrication of micellar nanoparticles for drug delivery through the self-assembly of block copolymers
Micelles formed through the self-assembly of block copolymers have been widely used to
encapsulate highly hydrophobic drugs to increase their effective solubility. However, this …
encapsulate highly hydrophobic drugs to increase their effective solubility. However, this …