Deconstructing cortical folding: genetic, cellular and mechanical determinants
C Llinares-Benadero, V Borrell - Nature Reviews Neuroscience, 2019 - nature.com
Folding of the cerebral cortex is a fundamental milestone of mammalian brain evolution and
is associated with dramatic increases in size and complexity. New animal models, genetic …
is associated with dramatic increases in size and complexity. New animal models, genetic …
Folding brains: from development to disease modeling
L Del-Valle-Anton, V Borrell - Physiological Reviews, 2022 - journals.physiology.org
The human brain is characterized by the large size and intricate folding of its cerebral cortex,
which are fundamental for our higher cognitive function and frequently altered in …
which are fundamental for our higher cognitive function and frequently altered in …
Single-cell analysis of long non-coding RNAs in the developing human neocortex
Abstract Background Long non-coding RNAs (lncRNAs) comprise a diverse class of
transcripts that can regulate molecular and cellular processes in brain development and …
transcripts that can regulate molecular and cellular processes in brain development and …
Evolution of the chordate telencephalon
SD Briscoe, CW Ragsdale - Current Biology, 2019 - cell.com
The dramatic evolutionary expansion of the neocortex, together with a proliferation of
specialized cortical areas, is believed to underlie the emergence of human cognitive …
specialized cortical areas, is believed to underlie the emergence of human cognitive …
Human-specific genomic signatures of neocortical expansion
Highlights•Human-specific aspects of cortical expansion.•Genomic changes affecting
cortical neurogenesis.•Human-specific genes affecting cortical progenitors.Neocortex …
cortical neurogenesis.•Human-specific genes affecting cortical progenitors.Neocortex …
Characterizing and comparing phylogenies from their Laplacian spectrum
Phylogenetic trees are central to many areas of biology, ranging from population genetics
and epidemiology to microbiology, ecology, and macroevolution. The ability to summarize …
and epidemiology to microbiology, ecology, and macroevolution. The ability to summarize …
Understanding the role of lncRNAs in nervous system development
BS Clark, S Blackshaw - Long Non Coding RNA Biology, 2017 - Springer
The diversity of lncRNAs has expanded within mammals in tandem with the evolution of
increased brain complexity, suggesting that lncRNAs play an integral role in this process. In …
increased brain complexity, suggesting that lncRNAs play an integral role in this process. In …
Brain long noncoding RNAs: multitask regulators of neuronal differentiation and function
S Keihani, V Kluever, EF Fornasiero - Molecules, 2021 - mdpi.com
The extraordinary cellular diversity and the complex connections established within different
cells types render the nervous system of vertebrates one of the most sophisticated tissues …
cells types render the nervous system of vertebrates one of the most sophisticated tissues …
The functions of long non-coding RNAs in neural stem cell proliferation and differentiation
Y Zhao, H Liu, Q Zhang, Y Zhang - Cell & Bioscience, 2020 - Springer
The capacities for neural stem cells (NSCs) self-renewal with differentiation are need to be
precisely regulated for ensuring brain development and homeostasis. Recently, increasing …
precisely regulated for ensuring brain development and homeostasis. Recently, increasing …
Posttranscriptional Control of Brain Development
The neocortex is among the newest evolutionary additions to the human brain, consistent
with its function in higher‐level processes such as cognition. This structure develops through …
with its function in higher‐level processes such as cognition. This structure develops through …