Deconstructing cortical folding: genetic, cellular and mechanical determinants

C Llinares-Benadero, V Borrell - Nature Reviews Neuroscience, 2019 - nature.com
Folding of the cerebral cortex is a fundamental milestone of mammalian brain evolution and
is associated with dramatic increases in size and complexity. New animal models, genetic …

Folding brains: from development to disease modeling

L Del-Valle-Anton, V Borrell - Physiological Reviews, 2022 - journals.physiology.org
The human brain is characterized by the large size and intricate folding of its cerebral cortex,
which are fundamental for our higher cognitive function and frequently altered in …

Single-cell analysis of long non-coding RNAs in the developing human neocortex

SJ Liu, TJ Nowakowski, AA Pollen, JH Lui… - Genome biology, 2016 - Springer
Abstract Background Long non-coding RNAs (lncRNAs) comprise a diverse class of
transcripts that can regulate molecular and cellular processes in brain development and …

Evolution of the chordate telencephalon

SD Briscoe, CW Ragsdale - Current Biology, 2019 - cell.com
The dramatic evolutionary expansion of the neocortex, together with a proliferation of
specialized cortical areas, is believed to underlie the emergence of human cognitive …

Human-specific genomic signatures of neocortical expansion

M Florio, V Borrell, WB Huttner - Current opinion in neurobiology, 2017 - Elsevier
Highlights•Human-specific aspects of cortical expansion.•Genomic changes affecting
cortical neurogenesis.•Human-specific genes affecting cortical progenitors.Neocortex …

Characterizing and comparing phylogenies from their Laplacian spectrum

E Lewitus, H Morlon - Systematic biology, 2016 - academic.oup.com
Phylogenetic trees are central to many areas of biology, ranging from population genetics
and epidemiology to microbiology, ecology, and macroevolution. The ability to summarize …

Understanding the role of lncRNAs in nervous system development

BS Clark, S Blackshaw - Long Non Coding RNA Biology, 2017 - Springer
The diversity of lncRNAs has expanded within mammals in tandem with the evolution of
increased brain complexity, suggesting that lncRNAs play an integral role in this process. In …

Brain long noncoding RNAs: multitask regulators of neuronal differentiation and function

S Keihani, V Kluever, EF Fornasiero - Molecules, 2021 - mdpi.com
The extraordinary cellular diversity and the complex connections established within different
cells types render the nervous system of vertebrates one of the most sophisticated tissues …

The functions of long non-coding RNAs in neural stem cell proliferation and differentiation

Y Zhao, H Liu, Q Zhang, Y Zhang - Cell & Bioscience, 2020 - Springer
The capacities for neural stem cells (NSCs) self-renewal with differentiation are need to be
precisely regulated for ensuring brain development and homeostasis. Recently, increasing …

Posttranscriptional Control of Brain Development

CM Musso, BM Lupan, DL Silver - Neocortical Neurogenesis in …, 2023 - Wiley Online Library
The neocortex is among the newest evolutionary additions to the human brain, consistent
with its function in higher‐level processes such as cognition. This structure develops through …