Worldwide emergence of fluconazole-resistant Candida parapsilosis: current framework and future research roadmap

F Daneshnia, JN de Almeida Júnior, M Ilkit… - The Lancet …, 2023 - thelancet.com
Candida parapsilosis is one of the most commen causes of life-threatening candidaemia,
particularly in premature neonates, individuals with cancer of the haematopoietic system …

COVID-19-associated candidiasis (CAC): an underestimated complication in the absence of immunological predispositions?

A Arastehfar, A Carvalho, MH Nguyen, MT Hedayati… - Journal of fungi, 2020 - mdpi.com
The recent global pandemic of COVID-19 has predisposed a relatively high number of
patients to acute respiratory distress syndrome (ARDS), which carries a risk of developing …

Antifungal heteroresistance causes prophylaxis failure and facilitates breakthrough Candida parapsilosis infections

B Zhai, C Liao, S Jaggavarapu, Y Tang, T Rolling… - Nature Medicine, 2024 - nature.com
Breakthrough fungal infections in patients on antimicrobial prophylaxis during allogeneic
hematopoietic cell transplantation (allo-HCT) represent a major and often unexplained …

The quiet and underappreciated rise of drug-resistant invasive fungal pathogens

A Arastehfar, C Lass-Flörl, R Garcia-Rubio… - Journal of Fungi, 2020 - mdpi.com
Human fungal pathogens are attributable to a significant economic burden and mortality
worldwide. Antifungal treatments, although limited in number, play a pivotal role in …

Candidemia: evolution of drug resistance and novel therapeutic approaches

AM Tortorano, A Prigitano, G Morroni… - Infection and Drug …, 2021 - Taylor & Francis
Candidemia and invasive candidiasis are the most common healthcare-associated invasive
fungal infections, with a crude mortality rate of 25–50%. Candida albicans remains the most …

[HTML][HTML] The changing epidemiology of fungal infections

C Lass-Flörl, S Steixner - Molecular Aspects of Medicine, 2023 - Elsevier
Invasive fungal diseases are common complications in critically ill patients and in those with
significant underlying imbalanced immune systems. Fungal co-, and/or super-infections are …

Gut mycobiota alterations in patients with COVID-19 and H1N1 infections and their associations with clinical features

L Lv, S Gu, H Jiang, R Yan, Y Chen, Y Chen… - Communications …, 2021 - nature.com
The relationship between gut microbes and COVID-19 or H1N1 infections is not fully
understood. Here, we compared the gut mycobiota of 67 COVID-19 patients, 35 H1N1 …

Candida parapsilosis complex in the clinical setting

M Govrins, C Lass-Flörl - Nature Reviews Microbiology, 2024 - nature.com
Representatives of the Candida parapsilosis complex are important yeast species causing
human infections, including candidaemia as one of the leading diseases. This complex …

Mechanisms of Pathogenic Candida Species to Evade the Host Complement Attack

DK Singh, R Tóth, A Gácser - Frontiers in cellular and infection …, 2020 - frontiersin.org
Candida species are common colonizers of the human skin, vagina, and the gut. As human
commensals, Candida species do not cause any notable damage in healthy individuals; …

Decreased echinocandin susceptibility in Candida parapsilosis causing candidemia and emergence of a pan-echinocandin resistant case in China

Y Ning, M Xiao, DS Perlin, Y Zhao, M Lu… - Emerging Microbes & …, 2023 - Taylor & Francis
Candida parapsilosis is becoming a predominant non-albicans cause of invasive
candidiasis (IC). Echinocandins are the preferred choice for IC treatment and prophylaxis …