Acylcarnitines: nomenclature, biomarkers, therapeutic potential, drug targets, and clinical trials
M Dambrova, M Makrecka-Kuka, J Kuka… - Pharmacological …, 2022 - Elsevier
Acylcarnitines are fatty acid metabolites that play important roles in many cellular energy
metabolism pathways. They have historically been used as important diagnostic markers for …
metabolism pathways. They have historically been used as important diagnostic markers for …
Betaine in inflammation: mechanistic aspects and applications
G Zhao, F He, C Wu, P Li, N Li, J Deng, G Zhu… - Frontiers in …, 2018 - frontiersin.org
Betaine is known as trimethylglycine and is widely distributed in animals, plants, and
microorganisms. Betaine is known to function physiologically as an important …
microorganisms. Betaine is known to function physiologically as an important …
[HTML][HTML] Betaine in human nutrition
SAS Craig - The American journal of clinical nutrition, 2004 - Elsevier
Betaine is distributed widely in animals, plants, and microorganisms, and rich dietary
sources include seafood, especially marine invertebrates (≈ 1%); wheat germ or bran (≈ …
sources include seafood, especially marine invertebrates (≈ 1%); wheat germ or bran (≈ …
The clinical significance of betaine, an osmolyte with a key role in methyl group metabolism
M Lever, S Slow - Clinical biochemistry, 2010 - Elsevier
Betaine is an essential osmolyte and source of methyl groups and comes from either the diet
or by the oxidation of choline. Its metabolism methylates homocysteine to methionine, also …
or by the oxidation of choline. Its metabolism methylates homocysteine to methionine, also …
Betaine and Trimethylamine-N-Oxide as Predictors of Cardiovascular Outcomes Show Different Patterns in Diabetes Mellitus: An Observational Study
M Lever, PM George, S Slow, D Bellamy, JM Young… - PloS one, 2014 - journals.plos.org
Background Betaine is a major osmolyte, also important in methyl group metabolism.
Concentrations of betaine, its metabolite dimethylglycine and analog trimethylamine-N …
Concentrations of betaine, its metabolite dimethylglycine and analog trimethylamine-N …
Betaine: a key modulator of one-carbon metabolism and homocysteine status
PM Ueland, PI Holm, S Hustad - Clinical Chemistry and Laboratory …, 2005 - degruyter.com
Betaine serves as a methyl donor in a reaction converting homocysteine to methionine,
catalysed by the enzyme betaine-homocysteine methyltransferase. It has been used for …
catalysed by the enzyme betaine-homocysteine methyltransferase. It has been used for …
Glycine betaine and glycine betaine analogues in common foods
In this study we have surveyed the betaine content of a wide range of foods commonly found
in the western diet. Glycine betaine, proline betaine (stachydrine), trigonelline and …
in the western diet. Glycine betaine, proline betaine (stachydrine), trigonelline and …
A review of pharmacological and pharmacokinetic properties of stachydrine
F Cheng, Y Zhou, M Wang, C Guo, Z Cao… - Pharmacological …, 2020 - Elsevier
Stachydrine is extracted from the leaves of Leonurus japonicus Houtt (or Motherwort,“Yi Mu
Cao” in Traditional Chinese Medicine) and is the major bioactive ingredient. So far …
Cao” in Traditional Chinese Medicine) and is the major bioactive ingredient. So far …
Metabolic biomarkers of prenatal disorders: an exploratory NMR metabonomics study of second trimester maternal urine and blood plasma
This work describes an exploratory NMR metabonomic study of second trimester maternal
urine and plasma, in an attempt to characterize the metabolic changes underlying prenatal …
urine and plasma, in an attempt to characterize the metabolic changes underlying prenatal …
Urinary biomarkers involved in type 2 diabetes: a review
A Matheson, MDP Willcox, J Flanagan… - … research and reviews, 2010 - Wiley Online Library
Diabetes mellitus is one of the most challenging health concerns of the 21st century. With at
least 30% of the diabetic population remaining undiagnosed, effective and early diagnosis is …
least 30% of the diabetic population remaining undiagnosed, effective and early diagnosis is …