The biology and clinical uses of blood stem cells

LB To, DN Haylock, PJ Simmons… - Blood, The Journal of …, 1997 - ashpublications.org
''It seems more than ever likely that blood-derived stem tive capacity. 47-49 In the allogeneic
setting, mobilized blood cells have also been used instead of BM. 50 Umbilical cord cells …

Biology of human umbilical cord blood-derived hematopoietic stem/progenitor cells

H Mayani, PM Lansdorp - Stem cells, 1998 - academic.oup.com
Reported in 1989, studies by Broxmeyer, Gluckman, and colleagues demonstrated that
umbilical cord blood (UCB) is a rich source of hematopoietic stem/progenitor cells (HSPC) …

The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ …

A Aiuti, IJ Webb, C Bleul, T Springer… - The Journal of …, 1997 - rupress.org
Hematopoietic progenitor cells migrate in vitro and in vivo towards a gradient of the
chemotactic factor stromal cell-derived factor-1 (SDF-1) produced by stromal cells. This is …

Stromal cells prevent apoptosis of AML cells by up-regulation of anti-apoptotic proteins

M Konopleva, S Konoplev, W Hu, AY Zaritskey… - Leukemia, 2002 - nature.com
The aim of this study was to study interactions between stromal bone marrow
microenvironment and leukemic cells. We tested the hypothesis that stromal cells prevent …

Aberrant overexpression of the Wilms tumor gene (WT1) in human leukemia

K Inoue, H Ogawa, Y Sonoda, T Kimura… - Blood, The Journal …, 1997 - ashpublications.org
To clarify whether the expression of the WT1 gene in leukemic cells is aberrant or merely
reflects that in normal counterparts, the expression levels of the WT1 gene were quantitated …

Constitutive expression of E-selectin and vascular cell adhesion molecule-1 on endothelial cells of hematopoietic tissues.

KM Schweitzer, AM Dräger… - The American journal …, 1996 - ncbi.nlm.nih.gov
The first step in the homing of hematopoietic progenitor cells (HPCs) from the peripheral
blood to the bone marrow involves an adhesion molecule-dependent contact with human …

JC virus infection of hematopoietic progenitor cells, primary B lymphocytes, and tonsillar stromal cells: implications for viral latency

MC Monaco, WJ Atwood, M Gravell… - Journal of …, 1996 - Am Soc Microbiol
The human polyomavirus JC virus (JCV) infects myelin-producing cells in the central
nervous system, resulting in the fatal demyelinating disease progressive multifocal …

Mesenchymal stem/progenitor cells developed in cultures from UC blood

SE Yang, CW Ha, MH Jung, HJ Jin, MK Lee… - …, 2004 - Taylor & Francis
Background Whether umbilical cord blood (UCB) serves as a source of mesenchymal
stem/progenitor cells (MSPC) is controversial. MSPC are the best candidates for cellular …

Lymphoid and myeloid differentiation of single human CD34+, HLA-DR+, CD38-hematopoietic stem cells

S Huang, LW Terstappen - 1994 - ashpublications.org
Multilineage differentiation of human fetal bone marrow CD34+ cell subsets was examined
using a single-cell liquid culture assay. Four CD34+ cell populations, ie,(1) CD38-, HLA …

Differentiation of natural killer (NK) cells from human primitive marrow progenitors in a stroma-based long-term culture system: identification of a CD34+ 7+ NK …

JS Miller, KA Alley, P McGlave - 1994 - ashpublications.org
We have recently described a marrow stroma-dependent long-term culture system that
supports differentiation of CD34+ human marrow primitive progenitors into natural killer (NK) …