Lipofuscin granules (LGs) are accumulated in the retinal pigment epithelium (RPE) cells.
The progressive LG accumulation can somehow lead to pathology and accelerate the aging …

Melanosomes, lipofuscin, and melanolipofuscin are the three principal types of pigmented
granules found in retinal pigment epithelium (RPE) cells. Changes in the density of …

The retinal pigment epithelium (RPE), which ensures the normal functioning of the neural
retina, is a pigmented single-cell layer that separates the retina from the Bruch's membrane …

It is known that during the process of aging, there is a significant decrease in the number of
melanosomes in the retinal pigment epithelium (RPE) cells in the human eye. Melanosomes …

Airway inflammation in asthma is related to increased reactive oxygen species generation,
potentially leading to tissue injury and subsequent airway remodeling. We evaluated …

Vitamins C and E and zeaxanthin are components of a supplement tested in a large clinical
trial—Age-Related Eye Disease Study 2 (AREDS2)—and it has been demonstrated that they …

Accumulation of lipofuscin in the retinal pigment epithelium (RPE) is a hallmark of aging and
is associated with retinal degeneration encountered in age-related macular degeneration …

Dehydrolutein accumulates in substantial concentrations in the retina. The aim of this study
was to compare antioxidant properties of dehydrolutein with other retinal carotenoids, lutein …

Curcumin is a plant‐derived yellow‐orange compound widely used as a spice, dye and food
additive. It is also believed to have therapeutic effects against different disorders. On the …

Retinal lipofuscin accumulates with age in the retinal pigment epithelium (RPE), where its
fluorescence properties are used to assess retinal health. It was observed that there is a …