Down syndrome is the most common form of intellectual disability and results from one of the
most complex genetic perturbations that is compatible with survival, trisomy 21. The study of …

α-Fetoprotein (AFP) measurements have clinical implications in fetal medicine and, in
infants and older children, in detection, differential diagnosis and monitoring of malignant …

Nominated for the Foundation of Sociology of Health and Illness Book Prize 2018 In the UK
and beyond, Down's syndrome screening has become a universal programme in prenatal …

Objective. Down syndrome (DS), also known as trisomy 21 syndrome, is a common and
most harmful congenital chromosomal genetic disease. This study is aimed at exploring the …

The primary embryonic signal in primates is chorionic gonadotropin (CG, designated hCG in
humans), that is classically associated with corpus luteum rescue and progesterone …

Prenatal examination plays an important role in present medical diagnosis. It provides
information on fetal health status as well as the diagnosis of fetal treatment feasibility. The …

In Turkey, the rate of consanguineous marriage is quite high (22–24%) and as a result, the
incidence of autosomal recessive diseases and congenital anomalies is also very high and …

Down's syndrome (DS) is the most common genetic cause of developmental delay with an
incidence of 1 in 800 live births, and is the predominant reason why women choose to …

Background: Among the genetics disorders, Down syndrome (DS) is the major cause of
mental retardation, congenital heart and intestinal disease. So far, no certain therapeutic …

目的: 采用血清三联[甲胎蛋白(AFP), 游离雌三醇(uE3), 总β 人绒毛膜促性腺激素(Total-βHCG)]
筛查19 730 名孕中期妇女, 以探讨三联筛查对唐氏综合征和18 三体综合征诊断的临床价值 …