[HTML][HTML] A systematic review of the evidence for deprescribing interventions among older people living with frailty
Background Older people living with frailty are often exposed to polypharmacy and potential
harm from medications. Targeted deprescribing in this population represents an important …
harm from medications. Targeted deprescribing in this population represents an important …
Model-informed precision dosing: background, requirements, validation, implementation, and forward trajectory of individualizing drug therapy
Model-informed precision dosing (MIPD) has become synonymous with modern approaches
for individualizing drug therapy, in which the characteristics of each patient are considered …
for individualizing drug therapy, in which the characteristics of each patient are considered …
Polypharmacy cutoff and outcomes: five or more medicines were used to identify community-dwelling older men at risk of different adverse outcomes
OBJECTIVE: This study aimed to determine an optimal discriminating number of
concomitant medications associated with geriatric syndromes, functional outcomes, and …
concomitant medications associated with geriatric syndromes, functional outcomes, and …
Too much medicine in older people? Deprescribing through shared decision making
Too much medicine in older people? Deprescribing through shared decision making Page 1 Too
much medicine in older people? Deprescribing through shared decision making Jansen and …
much medicine in older people? Deprescribing through shared decision making Jansen and …
Pharmacokinetics and drug metabolism in the elderly
U Klotz - Drug metabolism reviews, 2009 - Taylor & Francis
Aging involves progressive impairments in the functional reserve of multiple organs, which
might also affect drug metabolism and pharmacokinetics. In addition, the elderly population …
might also affect drug metabolism and pharmacokinetics. In addition, the elderly population …
Systematic review of anticholinergic risk scales in older adults
CE Durán, M Azermai, RH Vander Stichele - European journal of clinical …, 2013 - Springer
Background Anticholinergic drugs are often involved in explicit criteria for inappropriate
prescribing in older adults. Several scales were developed for screening of anticholinergic …
prescribing in older adults. Several scales were developed for screening of anticholinergic …
[HTML][HTML] Safe prescribing of non-steroidal anti-inflammatory drugs in patients with osteoarthritis–an expert consensus addressing benefits as well as gastrointestinal …
Background There are several guidelines addressing the issues around the use of NSAIDs.
However, none has specifically addressed the upper versus lower gastrointestinal (GI) risk …
However, none has specifically addressed the upper versus lower gastrointestinal (GI) risk …
[HTML][HTML] The advent of a new era in digital healthcare: a role for 3D printing technologies in drug manufacturing?
II Andreadis, CI Gioumouxouzis, GK Eleftheriadis… - Pharmaceutics, 2022 - mdpi.com
The technological revolution has physically affected all manufacturing domains, at the
gateway of the fourth industrial revolution. Three-dimensional (3D) printing has already …
gateway of the fourth industrial revolution. Three-dimensional (3D) printing has already …
High‐risk prescribing and incidence of frailty among older community‐dwelling men
Evidence about the association between treatment with high–risk medicines and frailty in
older individuals is limited. We investigated the relationship between high–risk prescribing …
older individuals is limited. We investigated the relationship between high–risk prescribing …
Drugs with anticholinergic properties, cognitive decline, and dementia in an elderly general population: the 3-city study
I Carrière, A Fourrier-Reglat, JF Dartigues… - Archives of internal …, 2009 - jamanetwork.com
Background Despite the high intake of medications with anticholinergic properties by
community-dwelling elderly persons, the effects on cognitive decline and dementia have …
community-dwelling elderly persons, the effects on cognitive decline and dementia have …