Heart failure (HF) with preserved ejection fraction (HFpEF) is a clinical syndrome associated
with poor quality of life, substantial health-care resource utilization, and premature mortality …

Abstract The Rochester Epidemiology Project (REP) has maintained a comprehensive
medical records linkage system for nearly half a century for almost all persons residing in …

Background Adrenal tumours are commonly encountered in clinical practice, but
epidemiological data mainly originate from referral centres. We aimed to determine …

Background: The incidence of isolated anterior cruciate ligament (ACL) tears in the general
population is not well defined. Purpose/Hypothesis: The purpose of this study was to define …

Background: Descriptive epidemiology of total joint replacement procedures is limited to
annual procedure volumes (incidence). The prevalence of the growing number of …

Importance A National Institute on Aging and Alzheimer's Association workgroup proposed a
research framework for Alzheimer disease in which biomarker classification of research …

Importance Heart failure (HF) is commonly referred to as an epidemic, posing major clinical
and public health challenges. Yet, contemporary data on its magnitude and implications are …

Introduction Blood‐based biomarkers of amyloid pathology and neurodegeneration are
entering clinical use. It is critical to understand what factors affect the levels of these markers …

Objective To estimate the annual incidence and prevalence of and frequency of mortality
associated with antiphospholipid syndrome (APS). Methods An inception cohort of patients …

Background & Aims The incidence and prevalence of inflammatory bowel diseases (IBD)
continue to increase worldwide. We sought to update incidence rates of Crohn's disease …