The geometry of the channel formed by nontoxic derivative of diphtheria toxin CRM197 in
lipid bilayer was determined using the dependence of single-channel conductance upon the …

The quickly emerged global COVID-19 pandemic raised a desperate need in the
development of protecting vaccines targeting this disease. Therefore, a generation of …

A key step in the mode of cytotoxic action of diphtheria toxin (Dt) is the transfer of its catalytic
domain (cd) from endosomes into the cytosol. the main activity in this process is performed …

Several mammalian species are resistant to diphtheria toxin (DT). The DT receptor, proHB-
EGF in resistant and sensitive species, has a different primary structure due to the amino …

The level of proHB-EGF expression on J774, Raji, KG-1 cells derived from different types of
human and mouse immune system cells under the standard in vitro culture conditions and …

Молекулярна імунологія–один із найважливіших напрямів сучасної біології і прямий
«нащадок» традиційної імунології–виникла, сформувалась і зробила найважливіші …

The aim of the research was to compare in vitro characteristics of reception of the natural
diphtheria toxin—DT and its nontoxic recombinant analogs—toxoids. For assessing ligand …

Accepted: 12 November 2021 the quickly emerged global cOVID-19 pandemic raised a
desperate need in the development of protecting vaccines targeting this disease. Therefore …

The aim of the study was to synthesize poly (D, L-lactide-co-glycolide) particles PLGA and
obtain their complexes with a non-toxic diphtheria toxin recombinant fragment subunit B …

The aim of the review was to analyze the literature data related to the application of a variety
of diphtheria toxin derivatives. Although the studies interaction with sensitive and resistant …