Association of betel nut with carcinogenesis: revisit with a clinical perspective

RN Sharan, R Mehrotra, Y Choudhury, K Asotra - 2012 - journals.plos.org
Betel nut (BN), betel quid (BQ) and products derived from them are widely used as a socially
endorsed masticatory product. The addictive nature of BN/BQ has resulted in its widespread …

Oral submucous fibrosis: a historical perspective and a review on etiology and pathogenesis

WM Tilakaratne, RP Ekanayaka… - Oral Surgery, Oral …, 2016 - Elsevier
Oral submucous fibrosis (OSF) is a chronic, insidious disease characterized by progressive
submucosal fibrosis of the oral cavity and the oropharynx. People affected by this disease …

Downregulated miR329 and miR410 promote the proliferation and invasion of oral squamous cell carcinoma by targeting Wnt-7b

SG Shiah, JR Hsiao, WM Chang, YW Chen, YT Jin… - Cancer research, 2014 - AACR
Abstract microRNA (miRNA) dysregulation contributes widely to human cancer but has not
been fully assessed in oral cancers. In this study, we conducted a global microarray analysis …

Betel-quid chewing with or without tobacco is a major risk factor for oral potentially malignant disorders in Sri Lanka: a case-control study

HK Amarasinghe, US Usgodaarachchi, NW Johnson… - Oral oncology, 2010 - Elsevier
We investigated the prevalence of, and risk factors for, oral potentially malignant disorders
(OPMDs) in rural Sri Lanka. A cross-sectional community-based study was conducted by …

Are there betel quid mixtures less harmful than others? A scoping review of the association between different betel quid ingredients and the risk of oral submucous …

N Cirillo, PH Duong, WT Er, CTN Do, MEH De Silva… - Biomolecules, 2022 - mdpi.com
Oral submucous fibrosis (OSF) is a potentially malignant condition of the oral cavity
characterized by progressive fibrosis of the submucosal tissues. OSF is typically associated …

Areca nut chewing: initiation, addiction, and harmful effects emphasizing the barriers and importance of cessation

IA Athukorala, WM Tilakaratne… - Journal of …, 2021 - Wiley Online Library
Areca nut is a highly addictive substance with carcinogenic properties and causes many
harmful effects to the human body. Alkaloids are the major chemicals found in areca nut, and …

Promoter Hypermethylation of Tumor-Suppressor Genes p16INK4a, RASSF1A, TIMP3, and PCQAP/MED15 in Salivary DNA as a Quadruple Biomarker Panel for …

C Liyanage, A Wathupola, S Muraleetharan, K Perera… - Biomolecules, 2019 - mdpi.com
Silencing of tumor-suppressor genes (TSGs) by DNA promoter hypermethylation is an early
event in carcinogenesis; hence, TSGs may serve as early tumor biomarkers. We determined …

Smokeless tobacco and oral potentially malignant disorders in South Asia: a systematic review and meta-analysis

Z Khan, S Khan, L Christianson… - Nicotine and …, 2017 - academic.oup.com
Abstract Oral Potentially Malignant Disorders (OPMDs) are chronic lesions or conditions
characterized by a potential for malignant transformation. While recent meta-analyses show …

Analysis of various risk factors affecting potentially malignant disorders and oral cancer patients of Central India

V Kadashetti, M Chaudhary, S Patil… - Journal of cancer …, 2015 - journals.lww.com
Aims: A case-control study was carried out to assess the prevalence and various risk factors
among potentially malignant disorders (PMD) and oral cancer patients of central India …

Correlation of salivary and serum IgG, IgA levels with total protein in oral submucous fibrosis

KA Patidar, RN Parwani, SP Wanjari - Journal of Oral Science, 2011 - jstage.jst.go.jp
Oral submucous fibrosis (OSMF) is a disabling, potentially malignant condition of the oral
cavity. The aetiology of OSMF is multifactorial but remains obscure. Although arecanut is …