Diagnosis of progressive multiple sclerosis from the imaging perspective: a review

M Filippi, P Preziosa, F Barkhof, DT Chard… - JAMA …, 2021 - jamanetwork.com
Importance Although magnetic resonance imaging (MRI) is useful for monitoring disease
dissemination in space and over time and excluding multiple sclerosis (MS) mimics, there …

Optical coherence tomography as a biomarker of neurodegeneration in multiple sclerosis: a review

R Alonso, D Gonzalez-Moron, O Garcea - Multiple sclerosis and related …, 2018 - Elsevier
Neurodegeneration is one the most important pathological factors which contributes to
permanent disability in multiple sclerosis (MS). Optical coherence tomography (OCT) …

Early diagnosis of multiple sclerosis by OCT analysis using Cohen's d method and a neural network as classifier

E Garcia-Martin, M Ortiz, L Boquete… - Computers in Biology …, 2021 - Elsevier
Background The consequences of inflammation, demyelination, axonal degeneration and
neuronal loss in the central nervous system, typical of the development of multiple sclerosis …

Retinal measurements predict 10‐year disability in multiple sclerosis

A Rothman, OC Murphy, KC Fitzgerald… - Annals of Clinical …, 2019 - Wiley Online Library
Objective Optical coherence tomography (OCT)‐derived measures of the retina correlate
with disability and cortical gray matter atrophy in multiple sclerosis (MS); however, whether …

Disease-modifying therapies for relapsing/active secondary progressive multiple sclerosis–a review of population-specific evidence from randomized clinical trials

A Bayas, M Christ, S Faissner… - Therapeutic …, 2023 - journals.sagepub.com
Although the understanding of secondary progressive multiple sclerosis (SPMS) is evolving,
early detection of relapse-independent progression remains difficult. This is further …

[HTML][HTML] Recent progress in the identification of early transition biomarkers from relapsing-remitting to progressive multiple sclerosis

S Maier, L Barcutean, S Andone, D Manu… - International Journal of …, 2023 - mdpi.com
Despite extensive research into the pathophysiology of multiple sclerosis (MS) and recent
developments in potent disease-modifying therapies (DMTs), two-thirds of relapsing …

Changes in volume of various retinal layers over time in early and intermediate age-related macular degeneration

A Lamin, JD Oakley, AM Dubis, DB Russakoff… - Eye, 2019 - nature.com
Purpose To evaluate longitudinally volume changes in inner and outer retinal layers in early
and intermediate age-related macular degeneration (AMD) compared to healthy control …

The loss of macular ganglion cells begins from the early stages of disease and correlates with brain atrophy in multiple sclerosis patients

AM Pietroboni, L Dell'Arti, M Caprioli… - Multiple Sclerosis …, 2019 - journals.sagepub.com
Background: The importance of neurodegeneration in multiple sclerosis (MS) is increasingly
well recognized. Objectives: To evaluate retinal pathology using optical coherence …

Serum neurofilament light chain and optical coherence tomography measures in MS: A longitudinal study

E Tavazzi, D Jakimovski, J Kuhle… - Neurology …, 2020 - AAN Enterprises
Objective To study the association between serum neurofilament light chain (sNfL) and
multiple optical coherence tomography (OCT) measures in patients with MS and healthy …

Effects of ibudilast on retinal atrophy in progressive multiple sclerosis subtypes: Post hoc analyses of the SPRINT-MS trial

H Ehrhardt, J Lambe, H Moussa, ES Vasileiou… - Neurology, 2023 - AAN Enterprises
Background and Objectives Ganglion cell+ inner plexiform layer (GCIPL) thinning,
measured by optical coherence tomography (OCT), reflects global neurodegeneration in …