Foundations of immunometabolism and implications for metabolic health and disease

GS Hotamisligil - Immunity, 2017 - cell.com
Highly ordered interactions between immune and metabolic responses are evolutionarily
conserved and paramount for tissue and organismal health. Disruption of these interactions …

Epithelial Nlrp10 inflammasome mediates protection against intestinal autoinflammation

D Zheng, G Mohapatra, L Kern, Y He, MD Shmueli… - Nature …, 2023 - nature.com
Unlike other nucleotide oligomerization domain-like receptors, Nlrp10 lacks a canonical
leucine-rich repeat domain, suggesting that it is incapable of signal sensing and …

Dysregulated invertebrate tropomyosin–dectin-1 interaction confers susceptibility to allergic diseases

N Gour, S Lajoie, U Smole, M White, D Hu… - Science …, 2018 - science.org
The key factors underlying the development of allergic diseases—the propensity for a
minority of individuals to develop dysfunctional responses to harmless environmental …

NLRP10 Enhances CD4+ T-Cell-Mediated IFNγ Response via Regulation of Dendritic Cell-Derived IL-12 Release

M Vacca, J Böhme, LP Zambetti… - Frontiers in …, 2017 - frontiersin.org
NLRP10 is a nucleotide-binding oligomerization domain-like receptor that functions as an
intracellular pattern recognition receptor for microbial products. Here, we generated a …

The AIM2 Inflammasome Is Activated In Astrocytes During EAE

WE Barclay - 2021 - search.proquest.com
The inflammasomes are a group of pattern recognition receptors (PRRs) with unique
characteristics and critical to innate immunity by translating microbial and damage signals …

What can I TIL you? Decoding TCR antigens.

SE Henrickson - Science Immunology, 2018 - science.org
What can I TIL you? Decoding TCR antigens. Page 1 Gour et al., Sci. Immunol. 3, eaam9841
(2018) 23 February 2018 SCIENCE IMMUNOLOGY | RESEARCH ARTICLE 1 of 14 ALLERGY …