The novel object recognition (NOR) task has emerged as a popular method for testing the
neurobiology of nonspatial memory in rodents. This task exploits the natural tendency of …

While knowledge of the composition and mode of action of bee and wasp venoms dates
back 50 years, the therapeutic value of these toxins remains relatively unexploded. The …

Endocannabinoids (eCBs) exert major control over neuronal activity by activating
cannabinoid receptors (CBRs). The functionality of the eCB system is primarily ascribed to …

Small-conductance Ca2+-activated K+ channels (SK channels) are widely expressed
throughout the central nervous system. These channels are activated solely by increases in …

Synaptic plasticity (eg, long-term potentiation [LTP]) is considered the cellular correlate of
learning. Recent optogenetic studies on memory engram formation assign a critical role in …

Rats and mice are attracted by novel objects. They readily approach novel objects and
explore them with their vibrissae, nose and forepaws. It is assumed that such a single …

The role of the hippocampus in object recognition memory processes is unclear in the
current literature. Conflicting results have been found in lesion studies of both primates and …

Progressive cognitive deficits that emerge with aging are a result of complex interactions of
genetic and environmental factors. Whereas much has been learned about the genetic …

Potassium channels are particularly important in determining the shape and duration of the
action potential, controlling the membrane potential, modulating hormone secretion …

Abstract Ca2+-activated K+ (KCa) channels of small (SK) and intermediate (IK) conductance
are present in a wide range of excitable and non-excitable cells. On activation by low …