The SLC39A family of metal transporters was identified through homologies with the Zrt-and
Irt-like (ZIP) proteins from yeast and plants. Of all the ZIP transporters, ZIP14 is arguably the …

Alternative splicing (AS) is a key process in which precursor RNAs produce different mature
RNAs, and the disorder of AS is a key factor in promoting cancer development. Compared …

Alternative splicing (AS) is assumed to be a pivotal determinant for the generation of diverse
transcriptional variants in cancer. However, the comprehensive dysregulation of AS and the …

Zinc (Zn), which is an essential trace element, is involved in numerous mammalian
physiological events; therefore, either a deficiency or excess of Zn impairs cellular …

Hepatocellular carcinoma (HCC) accounts for the majority of primary liver cancer cases, with
more than 850,000 new diagnoses per year globally. Recent trends in the United States …

Alternative splicing of precursor messenger RNA has been increasingly associated with
tumorigenesis. The serine/arginine-rich protein (SR) family plays key roles in the regulation …

Post-transcriptional modifications to coding and non-coding RNAs are unquestionably a
pivotal way in which human mRNA and protein diversity can influence the different phases …

Background Oral squamous cell carcinoma (OSCC) is one of the common cancers
worldwide. The lack of specific biomarkers and therapeutic targets leads to delayed …

One of the long-standing principles of molecular biology has been that DNA functions as a
template for transcription of messenger RNAs, which are eventually translated into a protein …

Background Breast cancer is amongst the 10 first causes of death in women worldwide.
Around 20% of patients are misdiagnosed leading to early metastasis, resistance to …