Stress and defense responses in plant secondary metabolites production
T Isah - Biological research, 2019 - SciELO Chile
In the growth condition (s) of plants, numerous secondary metabolites (SMs) are produced
by them to serve variety of cellular functions essential for physiological processes, and …
by them to serve variety of cellular functions essential for physiological processes, and …
Terpene synthases as metabolic gatekeepers in the evolution of plant terpenoid chemical diversity
PS Karunanithi, P Zerbe - Frontiers in plant science, 2019 - frontiersin.org
Terpenoids comprise tens of thousands of small molecule natural products that are widely
distributed across all domains of life. Plants produce by far the largest array of terpenoids …
distributed across all domains of life. Plants produce by far the largest array of terpenoids …
Oxetane ring formation in taxol biosynthesis is catalyzed by a bifunctional cytochrome P450 enzyme
Taxol is a potent drug used in various cancer treatments. Its complex structure has prompted
extensive research into its biosynthesis. However, certain critical steps, such as the …
extensive research into its biosynthesis. However, certain critical steps, such as the …
Expansion within the CYP71D subfamily drives the heterocyclization of tanshinones synthesis in Salvia miltiorrhiza
Y Ma, G Cui, T Chen, X Ma, R Wang, B Jin… - Nature …, 2021 - nature.com
Tanshinones are the bioactive nor-diterpenoid constituents of the Chinese medicinal herb
Danshen (Salvia miltiorrhiza). These groups of chemicals have the characteristic furan D …
Danshen (Salvia miltiorrhiza). These groups of chemicals have the characteristic furan D …
Advances in biosynthesis, regulation, and metabolic engineering of plant specialized terpenoids
DA Nagegowda, P Gupta - Plant Science, 2020 - Elsevier
Plant specialized terpenoids are natural products that have no obvious role in growth and
development, but play many important functional roles to improve the plant's overall fitness …
development, but play many important functional roles to improve the plant's overall fitness …
[HTML][HTML] Cytochrome P450 enzymes: a driving force of plant diterpene diversity
In plant terpene biosynthesis, oxidation of the hydrocarbon backbone produced by terpene
synthases is typically carried out by cytochrome P450 oxygenases (CYPs). The …
synthases is typically carried out by cytochrome P450 oxygenases (CYPs). The …
Expanding the terpene biosynthetic code with non-canonical 16 carbon atom building blocks
Humankind relies on specialized metabolites for medicines, flavors, fragrances, and
numerous other valuable biomaterials. However, the chemical space occupied by …
numerous other valuable biomaterials. However, the chemical space occupied by …
Applications of synthetic biology in medical and pharmaceutical fields
X Yan, X Liu, C Zhao, GQ Chen - Signal transduction and targeted …, 2023 - nature.com
Synthetic biology aims to design or assemble existing bioparts or bio-components for useful
bioproperties. During the past decades, progresses have been made to build delicate …
bioproperties. During the past decades, progresses have been made to build delicate …
Synthetic biology of plant natural products: From pathway elucidation to engineered biosynthesis in plant cells
X Zhu, X Liu, T Liu, Y Wang, N Ahmed, Z Li… - Plant Communications, 2021 - cell.com
Plant natural products (PNPs) are the main sources of drugs, food additives, and new
biofuels and have become a hotspot in synthetic biology. In the past two decades, the …
biofuels and have become a hotspot in synthetic biology. In the past two decades, the …
Carnosic acid and carnosol, two major antioxidants of rosemary, act through different mechanisms
M Loussouarn, A Krieger-Liszkay, L Svilar… - Plant …, 2017 - academic.oup.com
Carnosic acid, a phenolic diterpene specific to the Lamiaceae family, is highly abundant in
rosemary (Rosmarinus officinalis). Despite numerous industrial and medicinal …
rosemary (Rosmarinus officinalis). Despite numerous industrial and medicinal …